Place of Origin: | China |
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Brand Name: | Senwayer Brand |
Certification: | ISO, 9001, USP |
Model Number: | 130018-87-0 |
Minimum Order Quantity: | 10g |
Price: | Discount is possible if your order is big enough |
Packaging Details: | 10g, 20g, 50g , 100g, 500g. 1kg, 10kg |
Delivery Time: | within 2 working days |
Payment Terms: | T/T in advance, Money Gram, Western Union, Bank Transfer. |
Supply Ability: | 50KG / Month |
CAS: | 130018-87-0 | MF: | C32H40ClNO4 |
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Apparence: | White Crystalline Powder | Purity: | 99% |
Synonyms: | Fexofenadine; Allegra | Grade: | Pharma Grade |
High Light: | chemical raw material,medical raw material |
Pharmaceutical Fexofenadine Hydrochloride CAS 130018-87-0 Allegra Anti Histaminic
Quick detail
Name: | Fexofenadine hydrochloride |
CAS No.: | 153439-40-8 |
Formula: | C32H39NO4.HCl |
Molecular Weight: | 538.13 |
Synonyms: | Fexofenadine;Allegra;Carboxyterfenadine hydrochloride;Fexofenadine HCl;MDL 16,455A;Telfast; |
Melting Point: | 148-150 °C |
Boiling Point: | 697.3 °C at 760 mmHg |
Flash Point: | 375.5 °C |
Appearance: | off-white crystalline solid |
Description
Fexofenadine hydrochloride (trade name: Allegra) belongs to a second-generation antihistamine pharmaceutical drug. It is mainly used for the treatment of allergy symptoms including watery eyes, hay fever, nasal congestion, urticaria, runny nose, itching eyes/nose, sneezing, hives, and itching. It is a kind of selectively peripheral H1 blocker. Its mechanism of action in vivo is through preventing the histamine-mediated activation of the H1 receptors, thus alleviating the symptoms related to allergy. Compared to the first-generation antihistamine drug, it is less prone to penetrate the blood-brain barrier, reducing the possibility to cause side effects such as drowsiness.
Uses
This combination medication is used to temporarily relieve symptoms caused by thecommon cold, flu, or allergies. It contains 2 medications: fexofenadine andpseudoephedrine. Fexofenadine is an antihistamine that helps relieve watery eyes, itchy eyes/nose/throat, runny nose, and sneezing. Pseudoephedrine is a decongestantthat helps relieve stuffy nose and ear congestion symptoms.
This medication is not recommended for use in children under 12 years of age due to the large amount of pseudoephedrine in it.
Specifications
Item | Requirement | Results |
Description | White to off-white powder or crystalline powder; bitter taste, odorless | White crystalline powder |
chloride | The solution gives reaction of chloride | complies |
HPLC | The retention time of the main peak of the test solution corresponds to that of reference peak | complies |
IR | The infrared spectrum of the testing solution corresponds to that of reference solution | complies |
Residual on ignition | ≤0.1% max | 0.06% |
Heavy metals | Not more than 0.2% | complies |
Impurity B | Not more than 0.2% | Not detected |
Water | Not more than 0.5% | 0.34% |
Impurity A | Not more than 0.2% | 0.03% |
decarboxylated degradant | Not more than 0.15% | 0.05% |
Single impurity | Not more than 0.1% | 0.06% |
Total impurities | Not more than 0.5% | 0.2% |
Content of chloride | 6.45%~6.75% | 6.52% |
Assay(Calculated on the anhydrous basis) | Not less than98.0% and Not more than102.0% | 99.6% |
Conclusion:meet the USP Standard |