58-33-3 Medical Promethazine Hydrochloride HCl For Allergic Disorders Cure

Medical Promethazine Hydrochloride HCl Allergic Disorders Cure 58-33-3 White Powder
 
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Description

• Promethazine hydrochloride is a racemic compound.
• Promethazine hydrochloride, a phenothiazine derivative, is designated chemically as 10H-Phenothiazine-10-ethanamine, N,N,α-trimethyl-, monohydrochloride, (±)-with the following structural formula:
• Promethazine hydrochloride occurs as a white to faint yellow, practically odorless, crystalline powder which slowly oxidizes and turns blue on prolonged exposure to air. It is soluble in water and freely soluble in alcohol.
• Promethazine is a neuroleptic medication and first-generation antihistamine of the phenothiazine family. The drug has strong sedative and weak antipsychotic effects. It also reduces motion sickness and has antiemetic and anticholinergic properties (via its action on the Dopamine receptor D2). In some countries it is prescribed for insomnia when benzodiazepines are contraindicated.

Usage

Promethazine hydrochloride are useful for:

• Perennial and seasonal allergic rhinitis.
• Vasomotor rhinitis.
• Allergic conjunctivitis due to inhalant allergens and foods.
• Mild, uncomplicated allergic skin manifestations of urticaria and angioedema.
• Amelioration of allergic reactions to blood or plasma.
• Dermographism.
• Anaphylactic reactions, as adjunctive therapy to epinephrine and other standard measures, after the acute manifestations have been controlled.
• Preoperative, postoperative, or obstetric sedation.

Indications for Promethazine HCl:

Motion sickness. Perioperative nausea & vomiting.