58-33-3 Medical Promethazine Hydrochloride HCl For Allergic Disorders Cure

Basic Information
Place of Origin: China
Brand Name: Senwayer Brand
Certification: ISO, 9001, USP
Model Number: 58-33-3
Minimum Order Quantity: 10g
Price: Discount is possible if your order is big enough
Packaging Details: 10g, 20g, 50g , 100g, 500g. 1kg, 10kg
Delivery Time: within 2 working days
Payment Terms: T/T in advance, Money Gram, Western Union, Bank Transfer.
Supply Ability: 50KG / Month
Detail Information
CAS: 58-33-3 MF: C17H21ClN2S
Apparence: White Crystalline Powder Purity: 99%
Storage Condition: Keep In A Cool, Dry, Dark Location Usage: Allergic Disorders Cure Drugs
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Product Description

Medical Promethazine Hydrochloride HCl Allergic Disorders Cure 58-33-3 White Powder
Quick detail

promethazine hydrochloride
CAS No.: 58-33-3

10H-Phenothiazine-10-ethanamine, N,N,α-trimethyl-, monohydrochloride;

Promethazine hydrochloride; Promethazine Hydrochloride;



Exact Mass: 320.11100
Molecular Weight: 320.88000
PSA: 31.78000
LogP: 5.10640

Appearance: white or off white powder
Density: 1.131 g/cm3
Melting Point: 230-232ºC
Boiling Point: 403.7ºC at 760 mmHg
Flash Point: 198ºC
Storage Condition: Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.


  • Promethazine hydrochloride is a racemic compound.
  • Promethazine hydrochloride, a phenothiazine derivative, is designated chemically as 10H-Phenothiazine-10-ethanamine, N,N,α-trimethyl-, monohydrochloride, (±)-with the following structural formula:
  • Promethazine hydrochloride occurs as a white to faint yellow, practically odorless, crystalline powder which slowly oxidizes and turns blue on prolonged exposure to air. It is soluble in water and freely soluble in alcohol.
  • Promethazine is a neuroleptic medication and first-generation antihistamine of the phenothiazine family. The drug has strong sedative and weak antipsychotic effects. It also reduces motion sickness and has antiemetic and anticholinergic properties (via its action on the Dopamine receptor D2). In some countries it is prescribed for insomnia when benzodiazepines are contraindicated.


58-33-3 Medical Promethazine Hydrochloride HCl For Allergic Disorders Cure 0



Promethazine hydrochloride are useful for:

  • Perennial and seasonal allergic rhinitis.
  • Vasomotor rhinitis.
  • Allergic conjunctivitis due to inhalant allergens and foods.
  • Mild, uncomplicated allergic skin manifestations of urticaria and angioedema.
  • Amelioration of allergic reactions to blood or plasma.
  • Dermographism.
  • Anaphylactic reactions, as adjunctive therapy to epinephrine and other standard measures, after the acute manifestations have been controlled.
  • Preoperative, postoperative, or obstetric sedation.


Indications for Promethazine HCl:

Motion sickness. Perioperative nausea & vomiting.

1. Adult:


Motion sickness: 25mg 30–60mins before travel; may repeat in 8–12hrs; maintenance 25mg twice daily. Perioperative nausea & vomiting: 25mg; may give additional doses of 12.5–25mg at 4–6hr intervals.


2. Children:
<2yrs: see Contraindications. Motion sickness: ≥2yrs: 12.5–25mg twice daily. Perioperative nausea & vomiting: 0.5mg/lb or 25mg; may give additional doses of 12.5–25mg or 0.5mg/lb at 4–6hr intervals.

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