API Active Pharmaceutical Ingredients Antiemetic Domperidone CAS 57808-66-9

Healthy Domperidone For Anti-Vomiting Lactation Antiemetic CAS 57808-66-9 API Drugs
 
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Domperidone Description

1. A novel peripheral dopamine receptor antagonist that does not cross the blood-brain barrier; anti-emetic. Domperidone(Motilium) is a dopamine blocker and an antidopaminergic reagent.
2. Domperidone is a commonly used antiemetic and gastro-kinetic drug with its appearance being white to light yellow powder and bitter taste. It is almost insoluble in water, slightly soluble in ethanol, easily soluble in lactic acid as well as soluble in citrate. This product is a kind of peripheral dopamine receptor antagonists with strong action.
3. Domperidone can block the DA1 and DA2 receptor next to the synapses, antagonizing the inhibitory effect of dopamine on the postsynaptic cholinergic neurons of myenteric plexus and causing the stomach contractions. It can promote the motility and tension of digestive tract motility to return to normal function, promoting the emptying of stomach, increasing the motility of gastric antral and duodenum, coordinating the contraction of the pylorus as well as enhancing the esophageal peristalsis and the tension of the lower esophageal sphincter.

 
Domperidone Usage

DOMPERIDONE SIDE EFFECTS

1. Unusual production of breast milk in men and women,
2. breast enlargement in men and women,
3. lowering of sexual drive (libido) in men,
4. menstrual periods may be irregular or stop,
5. problems with vision,
6. development of a tremor,
7. imbalance.

If any of these persist or you consider them severe then inform your doctor or pharmacist.