99% Purity Hypoglycemic Agent Raw Material Drug Metformin HCL CAS 1115-70-4

Basic Information
Place of Origin: China
Brand Name: Senwayer Brand
Certification: ISO, 9001, USP
Model Number: 1115-70-4
Minimum Order Quantity: 10g
Price: Discount is possible if your order is big enough
Packaging Details: 10g, 20g, 50g , 100g, 500g. 1kg, 10kg
Delivery Time: within 2 working days
Payment Terms: T/T in advance, Money Gram, Western Union, Bank Transfer.
Supply Ability: 50KG / Month
Detail Information
CAS: 1115-70-4 MF: C4H12ClN5
Apparence: Amber Crystalline Powder Purity: 99%
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chemical raw material


medical raw material

Product Description

Hypolycemic Agent Pharmaceutical Raw Materials Metformin HCL CAS 1115-70-4 Drugs
Quick detail

Product Name: 1,1-Dimethylbiguanide hydrochloride
Synonyms: 1,1-dimethyl biguanidhydrochloride; diabefagos; diformin; dimethylbiguanidehydrochloride; Dimethyldiguanidinehydrochloride; gliformin;haurymellin;meguan
CAS: 1115-70-4
MF: C4H12ClN5
MW: 165.62
EINECS: 214-230-6
Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;API's;Miscellaneous Compounds;Aerobic Glycolysis (the Warburg Effect);Cancer Metabolism;Inhibitors and Activators of the AMPK pathway;Inhibitors of Aerobic Glycolysis (the Warburg Effect);Building Blocks;Cancer Research;Chemical Synthesis;Guanidines;Nitrogen Compounds;Organic Building Blocks;API;FORTAMET;Diabetes Research;InhibitorsMelting point223-226 °C(lit.)storage temp.Store at RTMerck13,5963


Metformin HCL Description:

Metformin is used with a proper diet and exercise program and possibly with othermedications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb.


Metformin HCL Application

  1. The product belongs to hypoglycemic agents. It can be used in patients with type Ⅱ diabetes to reduce fasting and postprandial hyperglycemia, HbAlc can be decreased by 1% to 2%, hypoglycemic mechanism of this product may be: I increase the sensitivity of peripheral tissues to insulin, increases insulin-mediated glucose utilization . II increase glucose utilization of non-insulin dependent tissues, such as brain, blood cells, kidney medulla, intestine, skin and the like. III inhibit hepatic gluconeogenesis effect, reduce hepatic glucose output. IV inhibit glucose uptake by intestinal cells.
  2. Indications: For mild diabetes.
  3. Metformin hydrochloride is an anti-diabetic agent, reducing blood glucose levels, and improving insulin sensitivity. Its metabolites (including the inhibition of hepatic gluconeogenesis) is activated through LKB1-AMPK (AMP-activated protein kinase) path.
  4. Hypoglycemic agents, it is used for non-insulin-dependent diabetes. Rat oral LD50 of 1000 mg/kg.


Metformin HCL Dosage

Available as metformin hydrochloride; dosage expressed in terms of the salt.

Individualize dosage carefully based on patient’s glycemic response and tolerance.


Biological Activity

Antidiabetic agent; lowers plasma glucose levels and improves insulin sensitivity. Inhibits hepatic gluconeogenesis via activation of the LKB1/AMPK pathway. Displays antiproliferative effects in cancer cell lines. 


99% Purity Hypoglycemic Agent Raw Material Drug Metformin HCL CAS 1115-70-4 0


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