| Place of Origin: | China |
|---|---|
| Brand Name: | Senwayer Brand |
| Certification: | ISO, 9001, USP |
| Model Number: | 52-01-7 |
| Minimum Order Quantity: | 10grams |
| Price: | Discount is possible if your order is big enough |
| Packaging Details: | 10g, 20g, 50g , 100g, 500g. 1kg, 10kg |
| Delivery Time: | within 2 working days |
| Payment Terms: | T/T in advance, Money Gram, Western Union, Bank Transfer. |
| Supply Ability: | 1000kg/month |
| CAS: | 52-01-7 | Apparence: | White Powder |
|---|---|---|---|
| Purity: | 99% | Storage: | Shading, Confined Preservation |
| Stock: | Enough Stock | Grade: | Pharma Grade |
| High Light: | weight loss steroids,fat burning drugs |
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Oral High Blood Pressure Treatment Raw Material Powder Spironolactone 52-01-7 API
Quick detail
| Name: | Spironolactone |
| CAS No.: | 52-01-7 |
| Formula: | C24H32O4S |
| Molecular Weight: | 416.62 |
| Synonyms: | Alderon;3-(3-Keto-7.alpha.-acetylthio-17.beta.-hydroxy-4-androsten-17.alph a.-yl)propionic acid lactone;Uractone;Spiro(17H-cyclopenta(a)phenauthrene-17,2-(3H)-furan);Xenalon;Pregn-4-ene-21-carboxylic acid |
| EINECS: | 200-133-6 |
| Density: | 1.24 g/cm3 |
| Melting Point: | 207-208 °C(lit.) |
| Boiling Point: | 597 °C at 760 mmHg |
| Flash Point: | 302.3 °C |
| Solubility: | practically insoluble in water |
| Appearance: | White to Off White Solid |
Spironolactone Description
Spironolactone is used in combination with other medicines to treat high blood pressure (hypertension) and heart failure. Lowering blood pressure can reduce the risk of strokes and heart attacks.
Spironolactone is also used to diagnose and treat hyperaldosteronism, a condition in which the adrenal gland produces too much hormone called aldosterone. This medicine may also be used to treat fluid retention (edema) in patients with congestive heart failure, liver cirrhosis, or a kidney disorder called nephrotic syndrome.
Spironolactone is a potassium-sparing diuretic (water pill). It prevents your body from absorbing too much salt and keeps your potassium levels from getting too low. This medicine is also used to treat or prevent hypokalemia (low potassium levels in the blood).
Treatment by Condition Related to spironolactone
Spironolactone Specification:
| Test Items | Specification | Test Results |
| Appearance | Almost white crystalline powder | Almost white crystalline powder |
| Identification | Meet the requirements | Meet the requirements |
| Melting range |
198℃~209℃ Between 198℃ and 209℃ |
205.0℃~207.0℃ |
| Specific rotation |
-33°~-37° Between -33° and -37° |
-35° |
| Loss on drying |
≤0.5% Not more than 0.5% |
0.2% |
| Limit of mercapto compounds | Meet the requirements | Meet the requirements |
| Ordinary impurities | Meet the requirements | Meet the requirements |
| Organic volatile impurities | Meet the requirements | Meet the requirements |
| Assay(on the dried basis) |
97.0%~103.0%(C24H32O4S) Between 97.0% and 103.0% |
98.99% |
| Conclusion | Meet the requirements of USP29 | |
Spironolactone Dosage
Spironolactone comes as 25 milligrams (mg), 50 mg, and 100 mg oral tablets.
Dosage depends on your health issue:
Primary hyperaldosteronism: 100 to 400 mg daily
Edema: 25 to 200 milligrams every day, for at least 5 days
Essential hypertension: 50 to 100 mg every day, for at least two weeks
Hypokalemia: 25 to 100 mg once daily
Severe heart failure: 25 mg once daily, which may be increased to 50 mg once daily or decreased to 25 mg once every other day, depending on your tolerance of the drug
