| Place of Origin: | China |
|---|---|
| Brand Name: | Senwayer Brand |
| Certification: | ISO, 9001, USP |
| Model Number: | 378-44-9 |
| Minimum Order Quantity: | 10grams |
| Price: | Discount is possible if your order is big enough |
| Packaging Details: | 10g, 20g, 50g , 100g, 500g. 1kg, 10kg |
| Delivery Time: | within 2 working days |
| Payment Terms: | T/T in advance, Money Gram, Western Union, Bank Transfer. |
| Supply Ability: | 1000kg/month |
| CAS: | 378-44-9 | MF: | C22H29FO5 |
|---|---|---|---|
| Apparence: | Almost White Powder | Purity: | 99% |
| Usage: | Anti - Inflammatory Medicine | Other Name: | Celestene;Prestwick_703 |
| High Light: | anti allergy medicine,anti histaminic drugs |
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Oral Corticosteroids Betamethasone 378-44-9 Anti - Inflammatory Medicine Powder
Quick detail
| Name: | Betamethasone |
| CAS No.: | 378-44-9 |
| Formula: | C22H29FO5 |
| Molecular Weight: | 434.50 |
| Synonyms: | Celestene;Prestwick_703;9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one;Rinderon A;Cidoten;beta-Methasone alcohol;Betamethazone;Bedifos; Prednisolone, 9-fluoro-16beta-methyl-;Betamamallet;Betamethasone (JP14/USP);9-alpha-Fluoro-16-beta-methylprednisolone;Betafluorene;9-Fluoro-11-beta,17,21-trihydroxy-16-beta-methylpregna-1,4-diene-3,20-dione; Betapredol;Visubeta; |
| EINECS: | 206-825-4 |
| Density: | 1.32 g/cm3 |
| Melting Point: | 235-237 °C |
| Boiling Point: | 568.2 °C at 760 mmHg |
| Flash Point: | 297.5 °C |
| Appearance: | white to off-white solid |
Introduction of Betamethasone
Betamethasone, belongs to adrenal corticosteroids, it is a isomer of dexamethasone , and the role of betamethasone is similiar to prednisolone and dexamethasone , it has anti-inflammatory, anti-rheumatic, anti-allergic and suppression of the immune and other pharmacological effects, its anti-inflammatory effect is stronger than dexamethasone, triamcinolone, hydrocortisone etc. ,
Betamethasone sodium retention effect is a hundred times more than hydrocortisone, in primary adrenal hypofunction, it can be used together with glucocorticoid for replacement therapy ,and it is used for preventing or inhibiting cell-mediated immune response, delaying allergic reactions and reducing the primary immune response expansion ,it is used for low renin and low aldosterone syndrome and autonomic neuropathy induced orthostatic hypotension.
Currently betamethasone is also used for the treatment of active rheumatoid arthritis, rheumatoid arthritis, lupus, severe bronchial asthma, severe dermatitis, acute leukemia, atopic dermatitis, eczema, neurodermatitis, seborrheic dermatitis, and pruritus and comprehensive treatment of certain infections.
Betamethasone Usage:
Technical Test Sheet (TTS) of Glucocorticoid Steroids Betamethasone
| Identification (B,C) | Complies with the Standard | Complies |
| Specific optical Rotation | +118°~+126° | +123.5° |
| Single impurity | Not more than 1.0% | 0.29% |
| impurity that ≥0.5% | Not more than one | Complies |
| total impurities | Not more than 2.0% | 0.64% |
| Loss on drying | Not more than 1.0% | 0.05% |
| Assay(UV, basis on drying) | 97.0%~103.0% | 98.8% |
| Methanol | Not more than 3000ppm | Complies |
| Ethyl acetate | Not more than 5000ppm | Complies |
| Acetone | Not more than 5000ppm | Complies |
| DMF | Not more than 880ppm | Complies |
| Dichloromethane | Not more than 600ppm | Complies |
| Chloroform | Not more than 60ppm | Complies |
| Particle Size | 100.0%<30um | Complies |
| Residue on ignition | Not more than 0.2% | 0.03% |
| Conclusion | Qualified | |
