| Place of Origin: | China |
|---|---|
| Brand Name: | Senwayer Brand |
| Certification: | ISO, 9001, USP |
| Model Number: | 50-02-2 |
| Minimum Order Quantity: | 10grams |
| Price: | Discount is possible if your order is big enough |
| Packaging Details: | 10g, 20g, 50g , 100g, 500g. 1kg, 10kg |
| Delivery Time: | within 2 working days |
| Payment Terms: | T/T in advance, Money Gram, Western Union, Bank Transfer. |
| Supply Ability: | 1000kg/month |
| CAS: | 50-02-2 | MF: | C22H29FO5 |
|---|---|---|---|
| Apparence: | Almost White Powder | Purity: | 99% |
| MW: | 392.461 | Density: | 1.3±0.1 G/cm3 |
| Boiling Point: | 568.2±50.0 °C At 760 MmHg | Melting Point: | 255-264ºC |
| Appearance: | White Crystalline Solid | ||
| High Light: | pharmaceutical raw chemical,api raw material |
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Medical Dexamethasone Decadron Active Pharmaceutical Ingredients CAS 50-02-2 Powder
Quick detail
Product Name: Dexamethasone
CAS: 50-02-2
MF: C22H29FO5
MW: 392.46
EINECS: 200-003-9
Appearance:White powder
Melting Point:262-264 °C(lit.)
Alpha:75 º (c=1, dioxane)
Refractive index:76 ° (C=1, Dioxane)
Storage temp. :2-8°C
Solubility:ethanol: 1 mg/mL
Water Solubility:10 mg/100 mL (25 ºC)
Product Categories: Active Pharmaceutical Ingredients;Antitumors for Research and Experimental Use;Biochemistry;Hydroxyketosteroids;Steroids;Intermediates & Fine Chemicals;Pharmaceuticals;Isotope Labeled Compounds;Steroid and Hormone;Pharmaceutical intermediate;API;MAXIDEX;Hormone Drugs;Mainly used for anti-inflammatory and allergy
Stability:Stable. Combustible. Incompatible with strong oxidizing agents, strong bases, acid anhydrides, acid chlorides. May be light sensitive.
Introduction of Dexamethasone
Dexamethasone is a corticosteroid hormone (glucocorticoid). This injectable form of dexamethasone is used when a similar drug cannot be taken by mouth or when a very fast response is needed, especially in patients with severe medical conditions.
Talk to your doctor about the risks and benefits of dexamethasone, especially if it is to be injected near your spine (epidural). Rare but serious side effects may occur with epidural use.
Dexamethasone Dosage
Doses of dexamethasone in eye drop, cream and other forms differ from patient to patient and depend on the condition being treated.
For oral forms, strengths range from 0.5 milligrams (mg) to 6 mg per tablet.
The prescribed dose depends on the medical condition. In general, dosage for oral solutions and tablets are:
For adults: 0.75 to 9 mg a day, adjusted as needed.
For children: 0.02 to 0.3 mg per kilogram (2.2 pounds) of body weight a day, spread out throughout the day.
The dose for intravenous and intramuscular injections ranges from 0.5 to 9 mg daily, but can be higher or lower.
Dexamethasone COA
| Test Items | Specification | Test Results | |
| Appearance | white oralmost white,crystalline powder | Conform | |
| Solubility | Freely soluble in water,practically insoluble or very slightly soluble in alcohol and in methylene chloride. | Conform | |
| Identification | A | The UV absorption spectrum of the sample shows an absorption maximum at 276nm.The specific absorbance at the Maximum is55 to 64. | Conform |
| B | Infraed absorption spectrophotometry. | Conform | |
| C | Chromatogram obtained with test solution (b) is similar in position color & size to the principal spot in the chromatogram obtained with the reference solution. | Conform | |
| D | An orange-red color develop in methylene chloride layer. | Conform | |
| E | It geves reaction (a) of sulphates. | Conform | |
| Appearance of solution | Solution S is clear and not more intensely coloured than reference solution in BY6. | Conform | |
| Optical rotation | -0.10° to +0.10°determined on solution S. | +0.01° | |
| Acidity or alkalinity | NMT 0.4ml of 0.01M HCL is required to change the color of the indicator to red. | Conform | |
| Related substances | Impurity J ≤0.20% | Conform | |
| Any other impurity ≤0.30% | Conform | ||
| Total impurity ≤1.0% | Conform | ||
| Boron | ≤50ppm | Conform | |
| Sulphated ash | ≤0.10% | 0.06% | |
| Loss on drying | ≤0.5% | 0.30% | |
| Assay(on dried basis) | 98.0~101.0% | 98.8% | |
| Conclusion | The test results above BP2009 | ||
