| Place of Origin: | China |
|---|---|
| Brand Name: | Senwayer Brand |
| Certification: | ISO, 9001, USP |
| Model Number: | 53-43-0 |
| Minimum Order Quantity: | 10grams |
| Price: | Discount is possible if your order is big enough |
| Packaging Details: | 10g, 20g, 50g , 100g, 500g. 1kg, 10kg |
| Delivery Time: | within 2 working days |
| Payment Terms: | T/T in advance, Money Gram, Western Union, Bank Transfer. |
| Supply Ability: | 1000kg/month |
| CAS: | 53-43-0 | Alias: | Dehydroepiandrosterone, DHEA, PRASTERONE |
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| Apparence: | Almost White Crystalline Powder | Purity: | 99% |
| Stock: | Enough Stock | Grade: | Pharma Grade |
| High Light: | anti inflammatory medications,anti histaminic drugs |
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Effective DHEA Dehydroepiandrosterone CAS 53-43-0 Anti Inflammatory Raw Material
Quick detail
Molecule structure of Dehydroepiandrosterone (CAS NO.53-43-0):
IUPAC Name: (3S,8R,9S,10R,13S,14S)-3-Hydroxy-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-one
Molecular Weight: 288.42442 g/mol
Molecular Formula: C19H28O2
Density: 1.12 g/cm3
Melting Point: 149-151 °C(lit.)
Boiling Point: 426.7 °C at 760 mmHg
Flash Point: 182.1 °C
Index of Refraction: 1.56
Molar Refractivity: 83.11 cm3
Molar Volume: 256.9 cm3
Polarizability: 32.94×10-24 cm3
Surface Tension: 44.4 dyne/cm
Enthalpy of Vaporization: 78.7 kJ/mol
Vapour Pressure: 4.54E-09 mmHg at 25 °C
Dehydroepiandrosterone Description
Dehydroepiandrosterone (DHEA), also known as androstenolone or prasterone, the chemical name of 3-β-hydroxyandrosta-5-en-17-ketone, is a retention of cholesterol. Its molecular formula is C19H28O2, with molecular weight of 288.41, melting point of 151 ℃~153 ℃, optical rotation of +5.5, and it is precursor of adrenal hormone secreted by human adrenal cortex network. Physiological activities of the drug are as follows: adjust obesity, anti-diabetes, anti-carcinogenic and viral infections, improve memory, immune response and stress response, reduce stress. It is an intermediate to produce steroid hormone, and it participates in the synthesis of multiple hormones of adrenal secretion.
Dehydroepiandrosterone Application:
| Antidiabetic: | DHEA has an effect of improving glucose tolerance and insulin levels, and it is anti-diabetic. |
| Anti-cortical disease: | Androstenolone could enhance activity of endocrine system, and reduce cortisol levels. It is also resistant to a variety of pathological processes. The symptoms have greatly improved after taking Androstenolone of systemic lupus erythematosus (SLE) patients, indicating that Androstenolone works on SLE disease. DHEA helps body get cortical antibodies. Androstenolone concentration in plasma is greatly related to variety of cortical diseases: the lower the concentration, the greater the risk of illness. |
| Immune response: |
DHEA could restore the damaged immune response, and improve immune function of T cell and B cell. DHEA plays an important role in improving the physiological activity of insulin-like growth factor (IGF-1). It is a potentially beneficial drug for the treatment of immunodeficiency.
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| Effect on sclerotin: | Prasterone itself can not affect the growth and differentiation of human osteoblasts directly, but can affect the growth and differentiation of osteoblasts by affecting the changes of 1, 25-dihydroxyvitamin D3. The effect of DHEA on sclerotin depends on the form of existence of sex hormones in osteocytes and their endocrine effects on osteoblasts. |
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Protein metabolism:
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DHEA is a protein that assimilates hormones and has the effect of promoting protein synthesis. According to Marrero and other studies, feeding mice with prasterone (0.45%) could increase their liver weight, and increase liver mitochondria by induced liver protein, so restoring RNA and protein synthesis. |
| Others: | Extensive clinical research of prasterone has been made on the treatment of menopausal syndrome, scleroderma, coronary heart disease, gout, psoriasis, AIDS and so on. The study also found that the pathogenesis of tuberculosis cytoplasm deformation is associated with concentration of adrenal cortex hormones and anti-adrenocorticotropic hormones; fetal plasma cortisol (Cortisol)/DHEA-S concentration has a great relationship with childbirth. |
