Pharmacological Clomifene Citrate , CLOMID 50-41-9 Anti Hormone Drugs Powder

Pharmacological Clomifene Citrate Anti-hormone Drugs CLOMID 50-41-9 White Powder

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Product Name: Clomiphene Citrate
Synonyms: SEROPHENE;PERGOTIME;CLOMPHID;CLOMID;CLOMIFENE CITRATE;CLOMIPHENE CITRATE;CLOMIPHENE CITRATE SALT;2-[4-(2-CHLORO-1,2-DIPHENYLETHENYL)-PHENOXY]-N,N-DIETHYLETHANAMINE CITRATE SALT
CAS: 50-41-9
MF: C32H36ClNO8
MW: 598.08
EINECS: 200-035-3
Product Categories: API;Intermediates & Fine Chemicals;Pharmaceuticals;Amines;Aromatics;Peptides;CLOMID

Clomifene Citrate Usage

1. The product is an anti-estrogen (fertility inducer) drug used for treating dysfunctional uterine bleeding, polycystic ovary, menstrual disorders and drug-induced amenorrhea and other gynecological diseases.

2. It is a kind of hormone drugs for treating luteal insufficiency, anovulatory infertility, dysfunctional uterine bleeding.

Clomifene Citrate COA:

Clomiphene Citrate Application

1. Ovulation induction: for the treatment of anovulatory or inadequate luteal malfunction; infertility women who hope for pregnancy. At the 3-5 days of menstrual bleeding or progesterone withdrawal bleeding, orally administrate 50 mg daily and continuously take for five days. Usually ovulation occurs at about 7 days after stopping drugs when having intercourse is easy to increase the pregnancy rate. If the dose can induce ovulation, the treatment can be repeated; if there is no ovulation, the daily dose can be increased to 100~150 mg with administration in twice upon an empty stomach for 5 consecutive days. 

2. Functional uterine bleeding, secondary amenorrhea or severe oligomenorrhea, and polycystic ovary syndrome: for people who ha menstruation, they should begin to take drug at the 5th day of menstrual; People without menstruation may start at any day or at the 5th day of the in artificial cycle with 1/d 50~100mg.

3. Male with low sperm and infertility: 25mg /d/per time; consecutively take for 25 days as one treatment course. Repeat it after stopping for five days until the sperm count reach normal standards; this process normally takes 3 to 12 courses. Male patients with no sperm should not apply clomiphene citrate for therapy.

4. Senile vaginitis and non-specific vaginitis: apply one tablets of clomiphene citrate per day; place it with vaginal suppositories (each tablets contains clomiphene 0.1 mg and chloramphenicol 250 mg) into the vagina with a week being a course; It is reported that it has better efficiency than chlorhexidine suppository.

5. Treatment of the anus, vulva, scrotum itching and eczema, dermatitis, chilblains, scabies; can apply 10% clomiphene citrate cream for treating affected area with a rapid efficacy, a long duration and high safety..

How does clomifene citrate work?

Clomifene citrate blocks the effect of the hormone oestrogen in your body. This blocking effect tricks your body into bumping up levels of two other hormones that are essential for ovulation.

These two other hormones are:
1. follicle-stimulating hormone (FSH)
2. luteinising hormone (LH)
FSH causes the eggs in your ovaries to ripen, ready for release. LH triggers the release of one or more mature eggs from the ovary follicles. The egg or eggs then move down into one of your fallopian tubes.

Related ANTI-ESTROGEN product: 

Clomifene Citrate Cook Recipes:

1 gram of Clomiphene Citrate
1 beaker suitable for holding the volume of liquids
7.6 ml of Glycerol
11.3 ml of 190 Proof Grain Alcohol

Clomid
Powder: per 1 gram of Clomiphene Citrate
Produces: Highest concentration made - 50 mg/ml

Requirements:
1 gram of Clomiphene Citrate
1 beaker suitable for holding the volume of liquids
8.4 ml of PEG 600
10.5 ml of 190 Proof Grain Alcohol

Clomifene Citrate Side effects

Within the prescribed dose range, adverse reactions of clomiphene citrate is not obvious, it does not affect the efficacy of treatment with overdose and long-term medication causing a increased adverse reactions such as the suppression of spermatogenesis in treating male infertility. The main adverse reactions seen in:

1 Vasomotor symptom: Some women may have hot flashes, sweating and other menopausal syndrome, which is related to the anti-estrogen effect of drugs; this can disappear after treatment, it can also be alleviated by increased administration of estrogen.

2. Abdominal symptoms: bloating, a sense of falling and ovulation pain; these symptoms are often associated with ovulation and ovarian enlargement; It is necessary to be subject to a medical examination to rule out the possibility of ovarian enlargement.

3. Ovarian enlargement and ovarian cysts: applying predetermined dose rarely cause enlarged ovaries; once ovarian enlargement occurs, discontinue treatment until restoring back into normal ovarian size; be sure the reduce the drug dose and duration in the next course of drug; once ovarian cysts appears, treatment should also be discontinued immediately in order to avoid ovarian hyperstimulation syndrome.

4. Visually impairment: a few people may get blurred vision, double vision, flashing lights, etc., 

5. Multiple pregnancies and teratogenic: it has been already demonstrated that clomiphene citrate can significantly increase the incidence of multiple births, so it is necessary to perform fetal reduction surgeries if necessary. 

6. Other adverse reactions are rare, mostly due to the long treatment causes, including nausea, vomiting, nervousness, fatigue, dizziness, headache, insomnia, breast swelling and pain, increased menstrual flow, atopic dermatitis, increased weight, polyuria, and mild alopecia which may disappear after treatment.