Natural Zidovudine Azidothymidine 30516-87-1 For HIV Research and Experimental

Natural Zidovudine Azidothymidine 30516-87-1 For HIV Research and Experimental

Quick detail

Zidovudine
English name Zidovudine
Chinese alias 3'- azide -3'- deoxythymidine; 3'- azide -3'- thymine deoxyriboside; 3'- azide deoxythymidine
CAS number: 30516-87-1
The molecular formula C10H13N5O4
A molecular weight of 267.2413
Melting point: 106-112 C
Solubility: 1-5 g/100 mL at 17 degrees C
Characteristics: a white or off white powder
Content: 97~102%
 

Basic information

Packing: 1)Aluminum Foil Bag: 100g, 500g, 1Kg 2)Fiber Drum: 25Kg
Delivery Method: HKEMS, DHL, TNT, UPS, FEDEX, EMS, China Air Post etc.
Clearance Rate: 100% Custom Pass, Diguised Package and Safe Delivery
Delivery Time: 5-14 Working Days, Tracking Number Available
Payment Terms: T/T, MoneyGram, Western Union and Bitcoin
Origin: Hubei Province, China
Brand Name: Senwayer Brand
Production Capacity:  1000Kg/Month

Zidovudine Description

Zidovudine (ZDV), also known as azidothymidine (AZT), is an antiretroviral medication used to prevent and treat HIV/AIDS. It reduces the replication of the virus and leads to improvements in both symptoms and blood tests. It can also be used to prevent HIV transmission, such as from mother to child during the period of birth or after a needle stick injury. Used by itself in HIV-infected patients, AZT slows HIV replication in patients, but does not stop it entirely. HIV may become AZT-resistant over time, and therefore AZT is now usually used in conjunction with other anti-HIV drugs in the combination therapy called highly active antiretroviral therapy (HAART).
It is of the nucleoside analog reverse-transcriptase inhibitor (NRTI) class. AZT inhibits the enzyme (reverse transcriptase) that HIV uses to synthesize DNA, thus preventing viral DNA from forming.
AZT was the first U.S. government-approved treatment for HIV, marketed under the brand name Retrovir. AZT is included in Combivir and Trizivir. It is included in the World Health Organization's Model List of Essential Medicines, which suggests the minimum medicinal needs for a basic health care system.
 

Zidovudine Usage

• Usage A potent and selective inhibitor of HIV-1 replication
• Usage antibacterial
• General Description Slightly off-white odorless powdery solid. Air & Water Reactions Dust may form an explosive mixture in air. Water soluble. Hydrolysis occurs in strongly basic solutions . .
• Use: used as an anti AIDS and disease resistant poison, Zidorf as the disease resistant poison, for AIDS or AIDS related syndrome patients and immunodeficiency virus (HIV) infection therapy. March 19, 1987, approved USA food and Drug Administration of the drug listing. Zidorf is the first in the world to get a American FDA approved the production of anti AIDS drugs, because of its curative effect is accurate, become "the composition of the most basic cocktail" therapy. The product is disease resistant poison, in vitro on retroviruses including human immunodeficiency virus (HIV) with high activity. In the infected cells by cell thymidine kinase phosphorylation of three phosphoric acid zidovudine, the latter can selectively inhibit HIV reverse transcriptase, leading to HIV chain synthesis stops to prevent HIV replication.

Attention pls 

Those who are allergic to the chemicals, pregnant women, severe infection, severe trauma patients before and after surgery and diabetic coma and insulin-dependent diabetes patients disabled.
 
1. severe liver and kidney dysfunction, should be reduced or caution.
 
2. ischemic heart disease, pituitary and adrenal insufficiency deputy, diarrhea, vomiting and malnutrition in patients with caution.
 
3. Elderly patients and children with caution.
 
4. Use the regular testing of blood glucose, while other hypoglycemic drugs such as insulin sensitizers, α- glucosidase inhibitors in combination to adjust the dosage.

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