| Place of Origin: | China |
|---|---|
| Brand Name: | Senwayer |
| Certification: | ISO 9001, GMP, USP, BP, CP |
| Model Number: | 38183-03-8 |
| Minimum Order Quantity: | 100g |
| Price: | Discount is possible if your order is big enough |
| Packaging Details: | foil bag |
| Delivery Time: | within 3 workdays |
| Payment Terms: | T/T in advance, Money Gram, Western Union, Bank Transfer., L/C |
| Supply Ability: | 1000pcs/month |
| CAS: | 38183-03-8 | Other Name: | 7,8-DHF |
|---|---|---|---|
| Appearance: | Powder | Grade Standard: | Medicine Grade |
| Sample: | Available | Function: | Weight Loss |
| Purity: | 99% Min | Delivery: | Prompt |
| High Light: | 38183-03-8 7 8 - Dihydroxy Flavones,8 - Dihydroxy Flavones White Crystalline Powder |
||
Name: 7,8-DIHYDROXY FLAVONE
English synonym: 7,8-DHF
CAS number: 38183-03-8
Molecular formula: C15H10O4
Molecular weight: 254.24
EINECS Number: 253-812-4
Description
Melting point: 243-246°C
Boiling point: 494.4±45.0°C (Predicted)
Density: 1.443±0.06g/cm3(Predicted)
Storage conditions: Inert atmosphere, Room Temperature
Solubility: DMSO:soluble 24mg/mL
Form: solid
Acidity coefficient (pKa): 6.86±0.40 (Predicted)
Therapeutic uses
7,8-Dihydroxyflavone (7,8-DHF) is a potent and selective TrkB receptor agonist (Kd≈320 nM). The TrkB receptor is the major signaling receptor for brain-derived neurotrophic factor. 7,8-Dihydroxyflavone is a biologically effective compound. After intraperitoneal injection or oral administration to mice, 7,8-Dihydroxyflavone can cross the blood-brain barrier and activate TrkB and its downstream PI3K/Akt and MAPK. 7,8-DHF promotes the viability of cortical neurons and reduces their apoptosis in traumatic brain injury. 7,8-DHF was administered 3 hours after injury, and 7,8-DHF could reduce tissue damage through the PI3K/Akt signaling pathway. Treatment with 7,8-DHF did not induce any significant toxic effects in mice, and chronic administration was not toxic to mice. 7,8-DHF has a strong therapeutic effect on Alzheimer's disease and can inhibit obesity by activating muscle TrkB.
Packaging & Shipping
1. As your requirements
2. Prompt shipment after receipt of your order confirmation
3. Transit could be DHL,UPS,TNT,EMS,Fedex,and so on.
4. For mass orders,it will be delivered by air or sea.
5. Depending on your location ,please allow 1-5 business days for your order to arrive.
6. For small order,please expect 3-7 days by UPS DHL EMS
7. For mass order,please allow 5-8 days by air,15-30 days by sea.
