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Narcotic Drugs Propofol Powder 99% Purity 2078-54-8

Basic Information
Place of Origin: China
Brand Name: Senwayer Brand
Certification: ISO, 9001, USP
Model Number: 404-86-4
Minimum Order Quantity: 10grams
Price: Discount is possible if your order is big enough
Packaging Details: 10g, 20g, 50g , 100g, 500g. 1kg, 10kg
Delivery Time: within 2 working days
Payment Terms: T/T in advance, Money Gram, Western Union, Bank Transfer.
Supply Ability: 1000kg/month
Detail Information
CAS: 404-86-4 Alias: Capsaicin
Apparence: Almost White Crystalline Powder Purity: 99%
Function: Weight Loss Grade: Pharma Grade
High Light:

99% Purity Propofol Powder

,

2078-54-8 Propofol Powder


Product Description

99% purity clear Propofol liquid painkiller injection use

Product name Propofol
Alias Diprivan; Disoprofol

2,6-diisopropylphenol


Molecular formula
C12H180
Molecular weight
178

Injection accessories: Excipients: soybean oil (for injection), propylene glycol, poloxamers.


This product is colorless or light yellow clear liquid. Also special smell. When the light becomes yellow, in case of high temperature quickly turns yellow. This product is very soluble in ethanol, ether or endone; minimally soluble in water. Relative density The relative density of this product (Chinese Pharmacopoeia 2000 edition two Appendix VI A) is 0.952 ~ 0.956. Refractive index The refractive index of this product (Chinese Pharmacopoeia 2000 edition two Appendix VI F) is 1.5124 ~ 1.5144. Freezing point The freezing point of this product (Central and Fujian Pharmacopoeia 2000 edition two Appendix VI D) 18 ~ 19 ° C.

Pharmacology
A short-acting alkyl anesthetics. After intravenous injection rapidly distributed in the body, can produce sleep within 40 seconds into the anesthesia quickly and smoothly. t1 / 2a is 1.8-8.3 minutes. May be in the liver after the main and glucuronic acid metabolism, metabolites excreted by urine for 34 ~ 60 minutes. Vd was 2.83L / kg, plasma protein binding rate of 97% ~ 98%. If combined with fentanyl, then the product of blood concentration. The analgesic effect of this product is weak, can reduce intracranial pressure, brain oxygen consumption and cerebral blood flow decreased. Inhibit the respiratory system, there may be temporary respiratory arrest; also inhibit the circulatory system, there may be lower blood pressure. This product anesthesia recovery rapidly, about 8 minutes, recovery may occur nausea, vomiting and headache
 


Product name


Propofol

CAS No.

2078-54-8

Outer Packing


25KG

Production date

2017.03.18

Shelf life

2019.09.17

Standard adopted


EP7.0

Items of analysis

Specification

Results


Appearance


Colorless or very light yellow clear liquid


Very light yellow clear liquid


Identification


IR


Conforms


Refractive index


1.5125-1.5145


1.5139


Impurity G


≤0.2%


Not detected


Impurity E


≤0.01%


Not detected


Any other impurity


≤0.05%


0.033%


Total impurities


≤0.3%


0.050%


Impurity J,K,L,O


≤0.05%


Conform


Assay


98.0-102.0%


99.51%

Conclusion

Qualified




Dosage:
It is advisable to adjust the dose at the time of administration [about 4 ml (40 mg) given daily to the average healthy adult] and to observe the patient's response until the clinical signs indicate onset of anesthesia. Most adult patients younger than 55 years of age require approximately 2.0-2.5 mg / kg of propofol; those who exceed this age will generally have less need; and ASA grade III and IV patients should be given less frequently, every 10 seconds 2 ml (20 mg).

Indications
For general anesthesia induction and maintenance. Often with epidural or spinal anesthesia at the same time, often with analgesics, muscle relaxants and inhalation anesthetics used. For outpatients.

Contraindications
Discontinued in patients with elevated intracranial pressure and cerebral circulation disorders; disabled in obstetric anesthesia.
 

Contact Details
Abby Xiang

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