| Place of Origin: | China |
|---|---|
| Brand Name: | Senwayer Brand |
| Certification: | ISO, 9001, USP |
| Model Number: | 144701-48-4 |
| Minimum Order Quantity: | 10grams |
| Price: | Discount is possible if your order is big enough |
| Packaging Details: | 10g, 20g, 50g , 100g, 500g. 1kg, 10kg |
| Delivery Time: | within 2 working days |
| Payment Terms: | T/T in advance, Money Gram, Western Union, Bank Transfer. |
| Supply Ability: | 1000kg/month |
| CAS: | 144701-48-4 | Apparence: | Almost White Crystalline Powder |
|---|---|---|---|
| Purity: | 99% | Usage: | Angiotensin Receptor Blocker API |
| Stock: | Enough Stock | Packing: | As Your Requirement |
| High Light: | pharmaceutical raw material,medical raw material |
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Telmisartan (INN) Angiotensin Receptor Blocker API CAS 144701-48-4 White Powder
Quick detail
| Product Name: | Telmisartan |
| Synonyms: | TU-199;TELMISARTAN;PRITOR;MICARDIS;BIBR 277;4'[(1,4'-DIMETHYL-2'-PROPYL[2,6'-BI-1H-BENZIMIDAZOL]-1'-YL)METHYL][1,1'-BIPHENYL]-2-CARBOXYLIC ACID;4'-[(1,4'-DIMETHYL-2'-PROPYL[2,6'-BI-H-BENZIMIDAZOL]-1'-YL)METHYL][1,1'-BIPHENYL]-2-CARBOXYLIC ACID;3-methoxy-8-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methyl sulfinyl]-2,7,9-triazabicyclo[4.3.0]nona-2,4,8,10-tetraene |
| CAS: | 144701-48-4 |
| MF: | C33H30N4O2 |
| MW: | 514.63 |
| EINECS: | 1592732-453-0 |
| Product Categories: | Pharmaceutical material and intermeidates;Active Pharmaceutical Ingredients;INTERMEDIATESOF;Antihypertensive;Imidazoles;(intermediates of telmisartan);Telmisartan;Hypertension;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Other Products;Hypertension.;CARADRIN |
Description
Telmisartan (INN) is an angiotensin II receptor antagonist (angiotensin receptor blocker, ARB) used in the management of hypertension.
Telmisartan Chemical Properties
Melting point 261-263°C
density 1.16
RTECS DV2037500
storage temp. Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility DMSO: >5 mg/mL at 60 °C
form solid
color white
Water Solubility insoluble
Merck 14,9129
Chemical Properties
White or off-white crystalline powder, odorless and tasteless. Soluble in chloroform, slightly soluble in methanol, very slightly soluble in acetone, practically insoluble in water. Slightly soluble in 0.1mol/L hydrochloric acid, soluble in 0.1mol/L sodium hydroxide.
Absorption coefficient(E1％1cm):509～541
Usage
| Uses | cardiotonic |
| Uses | Telmisartan is an angiotensin II receptor antagonist. |
| Uses | anti-cancer agent |
| Uses | Used alone or in combination with other classes of antihypertensives for the treatment of hypertension. Also used in the treatment of diabetic nephropathy in hypertensive patients with type 2 diabetes mellitus, as well as the treatment of congestive heart |
Specification
| Item | Specification | Result |
| Appearance | White or slightly yellowish crystalline powder | White crystalline powder |
| Solubility | Should meet the requirement | Conforms |
| IR Identification | Should correspond to the RS Infrared Absorption | Correspond to the reference substance |
| Appearance of solution | Should meet the requirement | Conforms |
| Loss on drying | ≤0.5% | 0.20% |
| Sulphated ash | ≤0.1% | Conforms |
| Melting point | 261 ºC -263 ºC | 261.1 ºC -262.2 ºC |
| Particle size | 90% Less than 200um | Conforms |
| Assay | 99.0%~101.0% | 99.9% |
| Conclusion | It conforms to European Pharmacopoeia 7.0 | |
