| Place of Origin: | China |
|---|---|
| Brand Name: | Senwayer Brand |
| Certification: | ISO, 9001, USP |
| Model Number: | 35943-35-2 |
| Minimum Order Quantity: | 10grams |
| Price: | Discount is possible if your order is big enough |
| Packaging Details: | 10g, 20g, 50g , 100g, 500g. 1kg, 10kg |
| Delivery Time: | within 2 working days |
| Payment Terms: | T/T in advance, Money Gram, Western Union, Bank Transfer. |
| Supply Ability: | 1000kg/month |
| CAS: | 35943-35-2 | Apparence: | White Powder |
|---|---|---|---|
| Purity: | 99% | Other Name: | Akt Inhibitor V Triciribine, API-2 Akt/PKB |
| Function: | Cancer Cure Drug | Stock: | Enough Stock |
| High Light: | anti cancer drugs,breast cancer drugs |
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Akt Inhibitor V Triciribine CAS 35943-35-2 API-2 Akt/PKB Signaling Cancer Cure Drugs
Quick detail
Product name : Triciribine
Description : Selective, potent inhibitor of Akt activation
Alternative names : API 2: NSC 154020: TCN
Biological description: Cell-permeable tricyclic nucleoside that inhibits the phosphorylation, activation and signalling of Akt. Selective over PKC, PKA, SGK and p38 pathways. Induces cell growth arrest and apoptosis in vitro.
Purity: > 98%
Description
A cell-permeable and reversible tricyclic nucleoside that selectively inhibits the cellular phosphorylation/activation of Akt1/2/3. It does not inhibit known upstream activators of Akt, i.e. PI3K or PDK. Exhibits little effect towards cellular signaling pathways mediated by PKC, PKA, SGK, Stat3, p38, ERK1/2, or JNK. Shown to preferentially induce apoptosis and growth arrest in cancer cells with aberrant Akt activity both in vitro (≥ 60% in cell proliferation at 20 µM) and in vivo (≥ 80% inhibition in tumor growth in mice at 1 mg/kg/day, i.p.). Also available in InSolution™ format.
| Properties | |
| Density: | 2.02g/cm3 |
| Boiling Point: | 718.5ºC at 760mmHg |
| Flash Point: | 388.3ºC |
| Refractive Index: | 1.928 |
Application
Akt Inhibitor V, Triciribine, CAS 35943-35-2, is a cell-permeable, selective, reversible inhibitor of the cellular phosphorylation/activation of Akt1/2/3.
Research areas
Signal Transduction Protein Phosphorylation Ser / Thr Kinases PKB / AKT Biochemicals Chemical Type Biochemicals Biochemicals Chemical Type Nucleoside Biochemicals Pharmacology Enzymes Kinase Akt Inhibitors Biochemicals Pharmacology Signaling Signal transduction PI3K/Akt signaling Akt Inhibitors Biochemicals Research Area Cancer Signal transduction PI3K/Akt signaling Akt Inhibitors
