Ibutamoren MK 677 Muscles Building SARM Powder , Oral Growth Hormone 159634 47 6

Basic Information
Place of Origin: China
Brand Name: Jusheng Brand
Certification: ISO, 9001, USP
Model Number: 159634-47-6
Minimum Order Quantity: 10grams
Price: Discount is possible if your order is big enough
Packaging Details: 10g, 20g, 50g , 100g, 500g. 1kg, 10kg
Delivery Time: within 2 working days
Payment Terms: T/T in advance, Money Gram, Western Union, Bank Transfer.
Supply Ability: 1000kg/month
Detail Information
CAS: 159634-47-6 Alias: MK-677 Ibutamoren,ostarine
Apparence: Almost White Crystalline Powder Purity: 99%
Usage: For Muscle Gaining Stock: Enough Stock
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Product Description

Ibutamoren MK-677 Muscles Building SARM Powder Oral Growth Hormone 159634-47-6


Quick detail

Ibutamoren (MK-677)

Synonyms:2-Amino-N-[(1R)-2-[1,2-dihydro-1-(methylsulfonyl)spiro[3H-indole-3,4'-piperidin]-1'-yl]-2-oxo-1-[(phenylmethoxy)methyl]ethyl]-2-methylpropanamide methanesulfonate;(R)-1'-(2-Methylalanyl-O-benzyl-D-seryl)-1-(Methylsulfonyl)-1,2-dihydrospiro[indole-3,4'-piperidine] Mesylate;Crescendo;IbutaMoren Mesylate

CAS: 159752-10-0

MF: C27H36N4O5S.CH4O3S

MW: 624.776

Chemical Properties:Pale Yellow Solid

Usage:It is a potent and tissue-selective androgen receptor modulator (SARM)


MK-677 Description


Ibutamoren is frequently discussed on online forums for its anabolic muscle-building properties. It is available over the counter and used by those wishing to increase their growth hormone levels.

However, clinical studies of this compound are relatively few. In the text below, we will highlight what is known about ibutamoren so far.

Ibutamoren (also known as ibutamoren mesylate or MK-677), promotes the secretion of the growth hormone (GH) and increases insulin-like growth factor 1 (IGF-1) [R, R].
3.  Ibutamoren increases growth hormone levels by mimicking the action of the hormone ghrelin and binding to one of the ghrelin receptors (GHSR) in the brain. Activated GHSR stimulates growth hormone release from the brain.


Benefits of Ibutamoren

1) Helps Build Muscles

Ibutamoren is frequently used as an anabolic substance, to increase lean body mass i.e. create bigger muscles. It is orally active and can be taken once a day. These are all benefits compared to other growth hormone stimulators.

As previously mentioned, ibutamoren increases growth hormone levels and IGF-1 [R, R]. Both growth hormone and IGF-1, in turn, increase muscle mass, muscle strength, and reduce body fat [R, R, R].

In healthy obese men, a two-month treatment with ibutamoren increased lean mass, and transiently increased basal metabolic rate (BMR) [R].

2) Reduce Muscle Wasting

In food-deprived healthy volunteers, ibutamoren reversed diet-induced protein loss [R], that could cause muscle wasting.

In elderly patients with hip fracture, ibutamoren improved gait speed, muscle strength and reduced the number of falls [R].

3)Increases Bone Density

Growth hormone (GH) increases bone turnover and eventually bone density [R]. However, because of the increased turnover in subjects treated with growth hormone, bone density can initially decrease before increasing [R]. Basically, it takes time (> 1 year) to see the bone density increase.

In healthy obese male volunteers, ibutamoren increased bone turnover [R].

In elderly adults, ibutamoren increased bone building, as measured by osteocalcin, a marker of bone turnover [R].

4) Improves Sleep

A study showed that in both younger and elderly subjects, ibutamoren improved sleep quality and REM (rapid eye movement) sleep duration [R].

Apart from scientific studies, there have been many reports of subjective improvements in sleep quality, across various online forums.

5) Combats Aging and May Increase Longevity

Growth Hormone (GH) secretion and muscle mass both decline from mid-puberty throughout life [R].

In a study in the elderly, daily ibutamoren increased GH and IGF-1 levels to those of healthy young adults without serious adverse effects [R]. IGF-1 is known to have beneficial effects on longevity [R, R].

6) Have Nootropic Effects Some people use ibutamoren as a nootropic because it acts on the ghrelin receptor, which has nootropic effects. You can read more about these effects in the post on ghrelin. Science is, however, yet to study if and how ibutamoren affects cognitive performance.
7) Beneficial in Treating Growth Hormone Deficiency Ibutamoren can increase growth hormone, IGF-1, and IGFBP-3 levels in children with growth hormone deficiency. Furthermore, these effects are achieved without changing the concentrations of prolactin, glucose, triiodothyronine (T3), thyroxine (T4), thyrotropin, cortisol or insulin [R].


Recommended Dosage

According to several studies, MK-677 Ibutamoren doses of between five milligrams to twenty five milligrams (5-25mgs) per day have really shown significant results. There are a few individuals who have shown great results with higher doses, but 5-25 mgs is what is recommended. In fact, if you are a beginner, it is highly advisable that you start with a dosage of five milligrams


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