| Place of Origin: | China |
|---|---|
| Brand Name: | Senwayer Brand |
| Certification: | ISO, 9001, |
| Model Number: | 56-54-2 |
| Minimum Order Quantity: | 1 KG |
| Price: | Discount is possible if your order is big enough |
| Packaging Details: | 10g, 20g, 50g , 100g, 500g. 1kg, 10kg |
| Delivery Time: | within 2 working days |
| Payment Terms: | T/T in advance, Money Gram, Western Union, Bank Transfer. |
| Supply Ability: | 1000kg/month |
| CAS: | 56-54-2 | Apparence: | White Crystalline Powder |
|---|---|---|---|
| Purity: | 99% | Stock: | Enough Stock |
| Packing: | As Your Requirement. | Stability: | Stable. Moisture-sensitive. |
| High Light: | pharmaceutical raw material,chemical raw material |
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Antiarrhythmic Raw Material Drug CAS 56-54-2 Conchinin API White Medical Powder
Quick detail
Product Name: Quinidine
Synonyms: (8R,9S)-6'-Methoxycinchonan-9-ol;(8r,9s)-quinidine;(95)-cinchonan-9-0;(9s)-6’-methoxycinchonan-9-ol;(9S)-6'-Methoxycinchonan-9-ol;2-Quinuclidinemethanol, alpha-(6-methoxy-4-quinolyl)-5-vinyl-;6-Methoxy-alpha-(5-vinyl-2-quinuclidinyl)-4-quinolinemethanol;6'-Methoxycinchonan-9-ol
CAS: 56-54-2
MF: C20H24N2O2
MW: 324.42
EINECS: 200-279-0
Exact Mass: 324.18400
PSA: 45.59000
LogP: 3.11110
Description
Quinidine is a commonly used class I antiarrhythmic drug. It is a stereoisomer of quinine, originally derived from the bark of the cinchona tree. It exerts its antiarrhythmic effects on the heart by interacting with the electrophysiology mechanisms that cause arrhythmias to modify the abnormalities in impulse initiation and conduction. Quinidine depresses normal automaticity in cardiac fibers that may act as ectopic pacemakers causing arrhythmias. Quinidine also blocks the slowly inactivating, tetrodotoxin-sensitive Na current, the slow inward calcium current (ICa), the rapid (IKr) and slow (IKs) components of the delayed potassium rectifier current, the inward potassium rectifier current (IKI), the ATP-sensitive potassium channel (IKATP) and Ito.
A dextrorotatory stereoisomer of Quinine. Antiarrhythmic (class IA). Antimalarial.
Properties
| Appearance : | white to light yellow crystal powder |
| Density: | 0.05 g/100 mL (20ºC) |
| Melting Point: | 170-175ºC |
| Boiling Point: | 495.9ºC at 760 mmHg |
| Flash Point: | 253.7ºC |
| Water Solubility: | 0.05 g/100 mL (20 ºC) |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| Storage Condition: | Keep containers tightly closed. Store protected from light. Store in a cool, dry area away from incompatible substances. |
Quinidine COA
| Item | Requirements |
Test Results |
| Description | A white or almost white crystalline powder |
white crystalline powder |
| Infrared spectrum appraisal | Complies |
Complies |
| Rotation | 250~255(ethanol) |
253 |
| Melting point | 169C~174C |
172C |
| Loss on drying | ≤1.00% |
0.60% |
| Sulfate | ≤500ppm |
Complies |
| Chloride | ≤250ppm |
Complies |
| Other quinine anhydrous | ≤1.50% |
0.40% |
| Residue on ignition | ≤0.10% |
0.05% |
| Heavy Metal | ≤10ppm |
Complies |
| Conclusion |
Meets the Requirement |
|
Safety Info
| RTECS: | VA4725000 |
| Hazard Class: | 6.1(b) |
| Safety Statements: | S22-S36 |
| HS Code: | 2933990090 |
| Packing Group: | III |
| WGK Germany: | 3 |
| RIDADR: | UN 2811 |
| Risk Statements: | R22 |
| Hazard Codes: | Xn |
