| Place of Origin: | China |
|---|---|
| Brand Name: | Senwayer Brand |
| Certification: | ISO, 9001, |
| Model Number: | 61-76-7 |
| Minimum Order Quantity: | 1 KG |
| Price: | Discount is possible if your order is big enough |
| Packaging Details: | 10g, 20g, 50g , 100g, 500g. 1kg, 10kg |
| Delivery Time: | within 2 working days |
| Payment Terms: | T/T in advance, Money Gram, Western Union, Bank Transfer. |
| Supply Ability: | 1000kg/month |
| CAS: | 61-76-7 | Apparence: | White Crystalline Powder |
|---|---|---|---|
| Purity: | 99% | Stock: | Enough Stock |
| Packing: | As Your Requirement. | Stability: | Stable. Moisture-sensitive. |
| High Light: | chemical raw material,medical raw material |
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Phenylephrine Hydrochloride Raw Material Powder CAS 61-76-7 Decongestant / Mydriatic
Quick detail
| Product Name: | Phenylephrine hydrochloride |
| Synonyms: | (-)-3-[1(R)-Hydroxy-2-(methylamino)ethyl]phenol hydrochloride;Phenylephrine Hydrochloride (200 mg);PHENYLEPHRINE HCL BP ((R)-3-HYDROXY-ALPHA-(METHYLAMINO) METHYL] BENZENEMETHANOLHYDROCHL ORIDE);)-3-Hydroxy-α-(methylaminomethyl)benzyl alcohol hydrochloride (R)-(−;Phenylephring Hydrochloride (R)-(−;(-)-alpha-hydroxy-beta-(methylamino)ethyl-alpha-(3-hydroxybenzene)hydrochlor;1-m-hydroxy-alpha-(methylaminomethyl)benzylalcoholhydrochloride;3-hydroxy-alpha-((methylamino)methyl)-,hydrochloride,(-)-benzenemethano |
| CAS: | 61-76-7 |
| MF: | C9H14ClNO2 |
| MW: | 203.67 |
| EINECS: | 200-517-3 |
| Product Categories: | Adrenergic Agents;pharmaceutical raw material;Pharmaceutical intermediates;Amines;Aromatics;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;API;AFRIN |
Description
Phenylephrine is a selective α1-adrenergic receptor agonist of the phenethylamine class used primarily as a decongestant, as an agent to dilate the pupil, and to increase blood pressure. Phenylephrine is marketed as an alternative for the decongestant pseudoephedrine, although clinical trials show phenylephrine, taken orally at the recommended dose, to be no more effective than placebo. Phenylephrine can also cause a decrease in heart rate through reflex bradycardia.
Phenylephrine Hydrochloride Medical uses
Phenylephrine is used as a decongestant sold as an oral medicine or as a nasal spray. It is a common ingredient in over-the-counter decongestants in the United States. Other decongestants include oxymetazoline and pseudoephedrine. Phenylephrine is used as an alternative for pseudoephedrine in decongestant medicines due to pseudoephedrine's use in the illicit manufacture of methamphetamine. Its efficacy as an oral decongestant has been questioned, with several recent independent studies finding that it provided no more relief to sinus congestion than a placebo.
Phenylephrine is commonly used as a vasopressor to increase the blood pressure in unstable patients with hypotension, especially resulting from septic shock. Such use is common in anesthesia or critical-care practices; it is especially useful in counteracting the hypotensive effect of epidural and subarachnoid anesthetics, as well as the vasodilating effect of bacterial toxins and the inflammatory response in sepsis and systemic inflammatory response syndrome. The elimination half life of phenylephrine is about 2.5 to 3.0 hours. The clinical effects of a single intravenous bolus dose of phenylephrine are short lived and needs to be repeated every 10–15 minutes. Commonly the drug is given as a carefully titrated intravenous infusion with a syringe pump or volumetric pump.
Properties
| Appearance | white to almost white crystalline powder |
| Melting Point: | 140-145ºC |
| Boiling Point: | 341.1ºC at 760 mmHg |
| Flash Point: | 163.4ºC |
| Refractive Index: | -45.5 ° (C=1, H2O) |
| Water Solubility: | >=10 g/100 mL at 21 ºC |
| Storage Condition: | Desiccate at RT |
Usage
| Uses | B-Adrenergic agonist. Mydriatic; decongestant. |
| Uses | DECONGESTANTS |
| Reactivity Profile | Phenylephrine hydrochloride is incompatible with acids, acid chlorides, acid anhydrides and oxidizing agents. Phenylephrine hydrochloride is also incompatible with butacaine, alkalis and ferric salts. |
Safety Info
| RTECS: | DO7525000 |
| Hazard Class: | 6.1(b) |
| Safety Statements: | S26-S37/39 |
| HS Code: | 2937229000 |
| Packing Group: | III |
| WGK Germany: | 3 |
| RIDADR: | UN 3249 |
| Risk Statements: | R22; R36/37/38 |
| Hazard Codes: | Xn |
