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Hydroxylamine Hydrochloride 5470-11-1 Active Pharmaceutical Ingredients Powder Azinous Acid

Basic Information
Place of Origin: China
Brand Name: Senwayer Brand
Certification: ISO, 9001, USP
Model Number: 5470-11-1
Minimum Order Quantity: 1KG
Price: Discount is possible if your order is big enough
Packaging Details: 25KG/bag, 55×90cm
Delivery Time: within 2 working days
Payment Terms: T/T in advance, Money Gram, Western Union, Bank Transfer.
Supply Ability: 1000kg/month
Detail Information
CAS: 5470-11-1 Apparence: White Crystal
Purity: ≥99% Packing: As Your Requirement
Storage Conditions: Avoid Light, Vacuum Airtight Preservation Stock: In Stock
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pharmaceutical raw material

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Product Description

Hydroxylamine Hydrochloride Pharmaceutical Intermediate CAS 5470-11-1 Powder

 


Quick detail


Hydroxylamine Hydrochloride
Molecular Formula: NH2OH·HCL
M.W.:69.5
Physicochemical properties: white crystal, easy deliquescence, soluble in water and glycerin, insoluble in ethanol and ethyl ether.
Specific gravity: (17/4οC) 1.67
Melting point: 152 οC (disassemble )
Use:This product is mainly used as a reducing agent and imaging agent, organic synthesis for the preparation of oxime, and also as the raw material for the synthesis of anti-cancer drugs (hydroxyurea), sulfa drugs (sinomin), anti-cold medicine and pesticide(methomyl). It is used as depolarizer In electro-analysis, in the synthetic rubber industry as non-staining short-term terminating agent, etc.
Production quality : Performance standards: Q/S BY001 - 2008

 

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Description


Hydroxylamine Hydrochloride is the hydrochloric acid salt of hydroxylamine. Hydroxylamine is a biological intermediate in the nitrification (biological oxidation of ammonia with oxygen into nitrite) and in the anammox (biological oxidation of nitrite and ammonium into dinitrogen gas) which are important in the nitrogen cycle in soil and in wastewater treatment plants.

 

Uses


Uses 1 .

 Hydroxylamine and its salts are commonly used as reducing agents in myriad organic and inorganic reactions. They can also act as antioxidants for fatty acids.

Uses 2. 

Conversion from cyclohexanone to caprolactam involving the Beckmann Rearrangement can be understood with this scheme.

Uses 3. 

 In the synthesis of nylon 6, cyclohexanone is first converted to its oxime; treatment of this oxime with acid induces the Beckmann rearrangement to give caprolactam :

The nitrate salt, hydroxylammonium nitrate, is being researched as a rocket propellant, both in water solution as a monopropellant and in its solid form as a solid propellant.

Uses 4 .

This has also been used in the past by biologists to introduce random mutations by switching base pairs from G to A, or from C to T. This is to probe functional areas of genes to elucidate what happens if their functions are broken. Nowadays other mutagens are used.

Uses 5 . 

Hydroxylamine can also be used to highly selectively cleave asparaginyl-glycine peptide bonds in peptides and proteins. It also bonds to and permanently disables (poisons) heme-containing enzymes. It is used as an irreversible inhibitor of the oxygen-evolving complex of photosynthesis on account of its similar structure to water.

Uses 6. 

This route also involves the Beckmann Rearrangement, like the conversion from cyclohexanone to caprolactam.
An alternative industrial synthesis of paracetamol developed by Hoechst–Celanese involves the conversion of ketone to a ketoxime with hydroxylamine.

 

Specification


Item

Spec 1

Spec 2

Spec 3

Appearance

White crystal

White crystal

White crystal

Content % ≥

98.00

99.00

99.00

Moisture % ≤

0.40

0.30

0.30

Sulphate % ≤

0.02

0.005

0.003

Fe % ≤

0.0005

0.0003

0.0003

Heavy metal% ≤

0.0005

0.0003

0.0003

 

Hydroxylamine Hydrochloride 5470-11-1 Active Pharmaceutical Ingredients Powder Azinous Acid 0 

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