Cancer Cure 10 Deacetylbaccatin

Basic Information
Place of Origin: China
Brand Name: Senwayer Brand
Certification: ISO, 9001, USP
Model Number: 32981-86-5
Minimum Order Quantity: 10grams
Price: Discount is possible if your order is big enough
Packaging Details: 10g, 20g, 50g , 100g, 500g. 1kg, 10kg
Delivery Time: within 2 working days
Payment Terms: T/T in advance, Money Gram, Western Union, Bank Transfer.
Supply Ability: 1000kg/month
Detail Information
CAS: 32981-86-5 Apparence: White Powder
Purity: 99% Other Name: 10-Deacetylbaccatin III, 10-DAB-III
Usage: Cancer Cure Grade: Pharma Grade
High Light:

anti cancer drugs


antineoplastic drugs

Product Description

Miscellaneous Natural Cancer Cure Drugs 10-Deacetylbaccatin III CAS 32981-86-5


Quick detail

Name: 10-Deacetylbaccatin
CAS No.: 32981-86-5
Formula: C29H36O10
Molecular Weight: 544.60
Synonyms: DESACETYLBACCATINE;BACCATIN III, 10-DEACETYL-;10-O-DEACETYLBACCATIN III;10-DAB-III;10-DEACETYLBACCATIN;12b-(Acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one;10-deacetylbaccatin11;10-deacetylbaccatiniii(extaxusbaccata)
Density: 1.41 g/cm3
Melting Point: 231-236 °C
Boiling Point: 716.8 °C at 760 mmHg
Flash Point: 233.5 °C
Solubility: Insoluble in water
Appearance: white solid


Hazard Codes T
Risk Statements 23/24/25
Safety Statements 45-38-36/37/39-28A
WGK Germany 3
HazardClass 6.1(b)
PackingGroup III


10-Deacetylbaccatin III Description:

1 10-Deacetylbaccatin III is a natural organic compound isolated from the bark of the Pacific yew tree (Taxus brevifolia) and related species.
2 10-Deacetylbaccatin III is used as a chemical intermediate in the preparation of the anti-cancer drug paclitaxel.
3 10-Deacetylbaccatins are a series of closely related natural organic compounds isolated from the Pacific yew tree (Taxus brevifolia) and related species.
4 10-Deacetylbaccatin III is a precursor to the anti-cancer drug docetaxel (Taxotere)
5 10-deacetylbaccatin III 10-O-acetyltransferase converts 10-deacetylbaccatin to baccatin III:


10-Deacetylbaccatin III Usage


10-DAB (10-Deacetylbaccatin) is an antineoplastic agent and an anti-cancer intermediate. 10-DAB (10-Deacetylbaccatin) has gained great attention because of its partly excellent anti-cancer properties.

10-DAB (10-Deacetylbaccatin) can be gained from the le

Usage 10-Deacetyl Baccatin III is an impurity of Paclitaxel (P132500) and derivatives.
Usage A intermediate in the synthesis of Taxol and derivatives


Biological Activity

10-deacetylbaccatin III is an intermediate in the biosynthetic pathway of the taxane, paclitaxel. Taxanes disrupt mitosis by preventing microtubule destabilization and spindle fiber formation in animal cells (Molè-Bajer, 1983). As a consequence of this mechanism, yew trees are slow growing organisms. Without mitosis, cells, especially cells with a high replication rate such as tumor cells, cannot divide. Taxanes are currently being investigated as possible treatment for certain cancers, and paclitaxel, is currently approved by the FDA for treatment of AIDS-related Karposi sarcoma, breast cancer, non-small cell lung cancer, and ovarian cancer.


Cancer Cure 10 Deacetylbaccatin 0

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