| Place of Origin: | China |
|---|---|
| Brand Name: | Senwayer Brand |
| Certification: | ISO, 9001, USP |
| Model Number: | 120511-73-1 |
| Minimum Order Quantity: | 10grams |
| Price: | Discount is possible if your order is big enough |
| Packaging Details: | 10g, 20g, 50g , 100g, 500g. 1kg, 10kg |
| Delivery Time: | within 2 working days |
| Payment Terms: | T/T in advance, Money Gram, Western Union, Bank Transfer. |
| Supply Ability: | 1000kg/month |
| CAS: | 120511-73-1 | Alias: | Anastrozole, Arimidex |
|---|---|---|---|
| Apparence: | Almost White Crystalline Powder | Purity: | 99% |
| Usage: | Anti Estrogen Steroid | Grade: | Pharma Grade |
| Stock: | Available | Delivery Time: | 5 TO 7 Working Days |
| High Light: | natural anti estrogen supplements,estrogen blocker supplement |
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Pharmaceutical Anastrozole Arimidex Anti Estrogen Steroid Hormone 120511-73-1
Quick detail
| Product name | Anastrozole, Arimidex, Breast Cancer Treatment Drugs |
| CAS : | 120511-73-1 |
| Molecular formula: | C17H19N5 |
|
Molecular weight:
|
293.37 |
| Appearance: | an off-white color crystalline powder |
| Purity: |
99%
|
| Product Categories | Active Pharmaceutical Ingredients;Antineoplastic;All Inhibitors;anti-neoplastic;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Anastrozole;API |
Anastrozole Usage :
1) It is the third-generation’s aromatase inhibitors, used for the treatment of advanced breast cancer of postmenopausal patients.
(2) Its used to cure the breast cancer.
(3) Anastrozole is the third-generation’s aromatase inhibitors, used for the treatment of advanced breast cancer of postmenopausal patients. It is an inhibitor for the triazole aromatase with a strong selectivity. It can inhibits aromatase which is prerequisite for the synthesis of pigment cells P-450 thereby blocking the biosynthesis of estrogens, and the estrogen is the essential part of the growth of breast cancer cells. Its used to cure the breast cancer, particularly suitable for postmenopausal women with advanced breast cancer who recrudescent after hormone adjuvant therapy.
This medication is used to treat breast cancer in women who have gone through "the change of life" (menopause). Anastrozole works by lowering estrogen hormone levels to help shrink tumors and slow their growth.
Usual Adult Dose for Breast Cancer
Initial dose: 1 mg orally taken once a day
Duration of therapy: Until tumor progression (treatment of advanced breast cancer); unknown (adjuvant treatment of early breast cancer)
Uses:
----Adjuvant treatment of postmenopausal women with hormone receptor-positive early breast cancer;
-----First-line treatment of postmenopausal women with hormone receptor-positive or hormone receptor unknown locally advanced or metastatic breast cancer;
-----Second-line treatment of advanced breast cancer in postmenopausal women with disease progression following tamoxifen therapy.
Renal Dose Adjustments
No adjustment recommended.
Liver Dose Adjustments
Mild to Moderate Hepatic Impairment: No adjustment recommended.
Stable Hepatic Cirrhosis: No adjustment recommended.
Severe Hepatic Impairment: Data not available.
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How to use Anastrozole
Take this medication by mouth with or without food, usually once a day, or as directed by your doctor.
Use this medication regularly in order to get the most benefit from it. Remember to use it at the same time each day.
Do not increase your dose or take this medication more often without your doctor's approval. Your condition will not improve any faster and the risk of serious side effects may be increased.
Since this drug can be absorbed through the skin, women who are pregnant or who may become pregnant should not handle or break the tablets of this medication.
Anastrozole Interactions
Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
This drug should not be used with the following medications because very serious interactions may occur: estrogens, tamoxifen.
If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting anastrozole.
Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use.
The COA of Anastrozole (arimidex):
| Items | Standard | Results |
| Description | White crystalline powder | Complies |
| Identification | IR HPLC Reactive |
Conform with standard IR Conform with standard HPLC Conform |
| Solubility | Freely soluble in methanol, acetone, ethanol and tetrahydrofuran. And very soluble in acetonitrile | Complies |
| Total Impurity | max.0.5% | 0.18% |
| Total Unspecified Impurity | max. 0.2% | 0.08% |
| Individual unspecified impurlty | max. 0.1% | 0.05% |
| Related compound B | max. 0.2% | 0.07% |
| Related compound C | max. 0.2% | 0.04% |
| Related compound D | max. 0.1% | 0.05% |
| Related compound E | max. 0.1% | 0.06% |
| Limit of cyclohexane | max. 0.08% | ND |
| Limit of ethylacetate | max. 0.1% | 0.07% |
| Melting point | 81.0~84.0ºC | 82.5~83.2ºC |
| Water | max. 0.3% | 0.21% |
| Residue on ignition | max. 0.1% | 0.07% |
| Heavy Metals | max.0.001% | Complies |
| Assay(HPLC) | 98.0%~102.0% | 99.8% |
| Storage | Cool and dry | |
| Conclusion | It complies to USP32 . | |
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Packaging & Delivery
1. Sufficient stock, so delivery promptly very day is OK after receive the payment.
2. Well-trained and disciplined packing team:provide unique& safe ways to ship 10g-100kg powers at one time to customers
3. Professional logistic agent We make sure of fast delivery and secure shipping.
4. Packing pictures and tacking code are provided within 24 hours after receiving the payment.Updated tracking information will be provided every other day.
