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Pharma Raw Materials Gemcitabine CAS 95058-81-4 Breast Cancer Ovarian Cure Drugs
4-AMINO-1-[(2R,4R,5R)-3,3-DIFLUORO-4-HYDROXY-5-(HYDROXYMETHYL)TETRAHYDROFURAN-2-YL]PYRIMIDIN-2-ONE; GEMCITABINE, FREE BASE; 2'-DESOXY-2',2'-DIFLUORCYTIDINE;
4-amino-1-[3,3-difluoro-4-hydroxy-5- (hydroxymethyl) tetrahydrofuran-2-yl]- 1H-pyrimidin- 2-one; 3-DEOXY-2,2-DIFLUORO-D-RIBOFURANOSE-3,5-DIBENZOATE
GEMCITABINE HCL; 2'-DEOXY-2',2'-DIFLUOROCYTIDINE; 1-(2-deoxy-2,2-difluoro-β-D-erythropentofuranosyl)cytosine; CYTIDINE, 2'-DEOXY-2',2'-DIFLUORO;
Gemcitabine, sold under the brand name Gemzar among others, is a chemotherapy medication used to treat a number of types ofcancer. This includes breast cancer, ovarian cancer, non-small cell lung cancer, pancreatic cancer, and bladder cancer. It is given by slow injection into a vein
|Ovarian Cancer||Gemcitabine in combination with carboplatin is indicated for the treatment of patients with advanced ovarian cancer that has relapsed at least 6 months after completion of platinum-based therapy.|
|Breast Cancer||Gemcitabine in combination with paclitaxel is indicated for the first-line treatment of patients with metastatic breast cancer after failure of prior anthracycline-containing adjuvant chemotherapy, unless anthracyclines were clinically contraindicated.|
|Non-Small Cell Lung Cancer||Gemcitabine is indicated in combination with cisplatin for the first-line treatment of patients with inoperable, locally advanced (Stage IIIA or IIIB), or metastatic (Stage IV) non-small cell lung cancer.|
Gemcitabine is indicated as first-line treatment for patients with locally advanced (nonresectable Stage II or Stage III) or metastatic (Stage IV) adenocarcinoma of the pancreas. Gemcitabine is indicated for patients previously treated with 5-FU.
Recommended Dose and Schedule
The recommended dose of Gemcitabine is 1,000 mg/m2 as an intravenous infusion over 30 minutes on Days 1 and 8 of each 21-day cycle, in combination with carboplatin AUC 4 intravenously after Gemcitabine administration on Day 1 of each 21-day cycle. Refer to carboplatin prescribing information for additional information.
How Gemcitabine Is Given
Gemcitabine is given by infusion through a vein (intravenously, by IV).
There is no pill form of Gemcitabine.
The amount of Gemcitabine you will receive depends on many factors, including your height and weight, your general health or other health problems, and the type of cancer you have. Your doctor will determine your exact dosage and schedule.