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|CAS:||54965-24-1||Alias:||Tamoxifen Citrate, Nolvadex|
|Apparence:||Almost White Crystalline Powder||Purity:||99%|
|Usage:||Anti Estrogen Steroid||Stock:||Enough Stock|
Safety Tamoxifen Citrate Nolvadex Powder For Anti Estrogen Steroid 54965-24-1
|Product Name:||Tamoxifen citrate|
|Melting point:||140-144 °C|
|storage temp. :||2-8°C|
|Water Solubility :||slightly soluble|
|Tamoxifen Citrate is a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Tamoxifen is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4.|
Nolvadex (tamoxifen citrate) is very comparable to Clomid, behaves in the same manner in all tissues, and is a mixed estrogen agonist/antagonist of the same type as Clomid. The two molecules are also very similar in structure. It is not correct that Nolvadex reduces levels of estrogen: Rather, it blocks estrogen from estrogen receptors and, in those tissues where it is an antagonist, causes the receptor to do nothing.
The claim that Nolvadex reduces gains should not be taken too seriously. The fact is that any number of bodybuilders have made excellent gains while using Nolvadex.
The belief that it reduces gains seems to stem from the fact that the scientific literature reports a slight reduction (individuals using anabolic steroids were not studied though) from use of Nolvadex.
1. Treatment of breast cancer.
2. Prevention of breast cancer.
3. Anti-tumor and anti-multidrug resistance.
By reducing membrane negotiability and enhancing rigidity of inter-cell binding site, Tamoxifen citrate can reduce concentration and activity of cancer metastasis promoter and various activating enzymes, so as to inhibit or hinder growth and metastasis of cancer cell. In addition, it can promote cells surrounding tumor focus to secrete a negative growth factor-transforming growth factor TGF-G, inhibiting multiply indefinitely of cancer cells; inhibiting oxidative damage of DNA bases which is caused by hydrogen peroxide generated from human neutrophils. So except for breast cancer, it is good for treatment and prevention of other malignant neoplasms, and is used for treatment of brain tumors, liver cancer, prostate cancer, etc. In addition, Tamoxifen citrate can reduce release effect of membrane P170 glycoprotein through reducing membrane negotiability, improving intracellular effective concentration of cytotoxic drug and reducing drug resistance.
4. Heart protection.
5. For the treatment of advanced and recurrent breast cancer and ovarian cancer
6. Anti-estrogen, protein kinase C inhibitor, beneficial cardiovascular effects, bone cancer treatment, induces DNA adduct formation
Tamoxifen citrate COA:
|Results Of Analysis Tests|
|Appearance||White or almost white powder||Conforms|
|Identification||UV conforms to RS||conforms|
|Loss on drying||≤0.5%||0.21%|
|Residue on ignition||≤0.2%||0.06%|
|Related substances||Total: Not more than 1.0%||0.32%|
|Individual: Not more than 0.5%||0.14%|
|Organic volatile impurities||conforms||conforms|
|Conclusion||Conform with USP 30|
Related ANTI-ESTROGEN product:
|Tamoxifen Citrate (Nolvadex)||CAS:54965-24-1|
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