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High Purity Dasatinib monohydrate Antineoplastic Cancer Cure Drug 863127-77-9

Good quality Anti Aging Drugs for sales
Good quality Anti Aging Drugs for sales
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High Purity Dasatinib monohydrate Antineoplastic Cancer Cure Drug 863127-77-9

China High Purity Dasatinib monohydrate Antineoplastic Cancer Cure Drug 863127-77-9 supplier
High Purity Dasatinib monohydrate Antineoplastic Cancer Cure Drug 863127-77-9 supplier High Purity Dasatinib monohydrate Antineoplastic Cancer Cure Drug 863127-77-9 supplier High Purity Dasatinib monohydrate Antineoplastic Cancer Cure Drug 863127-77-9 supplier

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Product Details:

Place of Origin: China
Brand Name: Jusheng Brand
Certification: ISO, 9001, USP
Model Number: 863127-77-9

Payment & Shipping Terms:

Minimum Order Quantity: 10grams
Price: Discount is possible if your order is big enough
Packaging Details: 10g, 20g, 50g , 100g, 500g. 1kg, 10kg
Delivery Time: within 2 working days
Payment Terms: T/T in advance, Money Gram, Western Union, Bank Transfer.
Supply Ability: 1000kg/month
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Detailed Product Description
CAS: 863127-77-9 Alias: Dasatinib Monohydrate, Dasatinib Hydrate
Apparence: Almost White Crystalline Powder Purity: 99.5%
Stock: Enough Stock Grade: Pharma Grade

High Purity Dasatinib monohydrate Antineoplastic Cancer Cure Drug 863127-77-9


Quick detail


Product Name: Dasatinib monohydrate
Synonyms: dasatinib monohydrate;n-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide monohydrate;n-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide;Dasatinib(TINIBS);N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide monohydrate;Dastinib;Bms 35482503;Dasatinib hydrate
CAS: 863127-77-9
MF: C22H28ClN7O3S
MW: 506.02082
EINECS:
Product Categories: Molecular Targeted Antineoplastic;API;SPRYCEL;Anti-cancer&immunity;Inhibitors


Basic information


Jusheng Packing: 1)Aluminum Foil Bag: 100g, 500g, 1Kg 2)Fiber Drum: 25Kg
Jusheng Delivery Method: HKEMS, DHL, TNT, UPS, FEDEX, EMS, China Air Post etc.
Jusheng Clearance Rate: 100% Custom Pass, Diguised Package and Safe Delivery
Jusheng Delivery Time: 5-14 Working Days, Tracking Number Available
Jusheng Payment Terms: T/T, MoneyGram, Western Union and Bitcoin
Jusheng Origin: Hubei Province, China
Jusheng Brand Name: Jusheng Brand
Jusheng Production Capacity:  1000Kg/Month

 

Dasatinib monohydrate​ Description


Dasatinib is an oral dual BCR/ABL and Src family tyrosine kinase inhibitor approved for use in patients with chronic myelogenous leukemia (CML). The main targets of Dasatinib, are BCRABL, SRC, Ephrins and GFR.

 

For the treatment of adults with chronic, accelerated, or myeloid or lymphoid blast phase chronic myeloid leukemia with resistance or intolerance to prior therapy. Also indicated for the treatment of adults with Philadelphia chromosome-positive acute lymphoblastic leukemia with resistance or intolerance to prior therapy.

 

Mechanism of action :


Dasatinib, at nanomolar concentrations, inhibits the following kinases: BCR-ABL, SRC family (SRC, LCK, YES, FYN), c-KIT, EPHA2, and PDGFRβ. Based on modeling studies, dasatinib is predicted to bind to multiple conformations of the ABL kinase. In vitro, dasatinib was active in leukemic cell lines representing variants of imatinib mesylate sensitive and resistant disease. Dasatinib inhibited the growth of chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL) cell lines overexpressing BCR-ABL. Under the conditions of the assays, dasatinib was able to overcome imatinib resistance resulting from BCR-ABL kinase domain mutations, activation of alternate signaling pathways involving the SRC family kinases (LYN, HCK), and multi-drug resistance gene overexpression.

 

How to proceed order


  1. Please let me know the items you are looking for, quantity, and the destination country.
  2. You confirm all details, and offer us purchasing order;
  3. We send the detail price of our product and offer the suitable shipping method for reference.
  4. You confirm the order and pay money 100% in advance and send us the detail address.
  5. We arrange the shipment according to your requirements.
  6. We offer after-sales service after you receive parcel.

 

Contact Details
Hubei Jusheng Technology Co., Ltd.

Contact Person: linda

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