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|CAS:||71251-02-0||Other Name:||Octenidine Dihydrochloride, Octenidine, Win 41464-2|
|Usage:||Modern Antiseptic Powder||Grade:||Pharma Grade|
Pain Killer Pharmaceutical Octenidine CAS 71251-02-0 Modern Antiseptic Powder
Product name:Octenidine Dihydrochloride
Molecular Formula: C36H62N42HCl
Use :It is a substitute for chlorhexidine, with respect to its slow action and concerns about the carcinogenic impurity 4-chloroaniline. Octenidine antiseptics often contain phenoxyethanol.
Octenidine dihydrochloride is a cationic surfactant, with a gemini-surfactant structure, derived from pyridine, active against Gram-positive and Gram-negative bacteria.
Since 1987, octenidine has been used in Europe as an antiseptic, in concentrations of 0.1 to 2.0%. It is a substitute for chlorhexidine, with respect to its slow action and concerns about the carcinogenic impurity 4-chloroaniline. Octenidine preparations are less expensive than chlorhexidine and no resistance had been observed as of 2007. They may contain the antiseptic phenoxyethanol.
Octenidine dihydrochloride (octenidine) was introduced for skin, mucous membrane and wound antisepsis more than 20 years ago. Until now, a wealth of knowledge has been gained, including in vitro and animal studies on efficacy, tolerance, safety and clinical experience both from case reports and prospective controlled trials. Nowadays, octenidine is an established antiseptic in a large field of applications and represents an alternative to older substances such as chlorhexidine, polyvidone-iodine or triclosan.
KEYWORD : wounds, antisepsis, disinfection, skin, mucous membranes, EN 1040, EN 1275, DIN 58940, MIC, MBC, microbistatic, microbicidal
Topic: anti-infective agents, local antisepsis chlorhexidine povidone-iodine suspensions triclosan mucous membrane chlorhexidine gluconate antimicrobials methicillin-resistant staphylococcus aureus malnutrition-inflammation-cachexia syndrome
Octenidine dihydrochloride is active against Gram-positive and Gram-negative bacteria.
In vitro suspension tests with 5 minute exposure time have shown that octenidine requires lower effective concentrations than chlorhexidine to kill common bacteria like Staphylococcus aureus, Escherichia coli, Proteus mirabilis and the yeast Candida albicans.