Payment & Shipping Terms:
|Stock:||Enough Stock||MOQ:||As Your Requirements|
8-Methoxypsoralen Anti Inflammatory Medicine Antipsoriatic Methoxsalen 298-81-7
Product Name: 8-Methoxypsoralen
Synonyms: 2-g)(1)benzopyran-7-one,9-methoxy-7h-furo(;2-g]benzopyran-7-one,9-methoxy-7h-furo[;5-Benzofuranacrylic acid, 6-hydroxy-7-methoxy-, delta-lactone;5-Benzofuranacrylicacid,6-hydroxy-7-methoxy-,δ-lactone;6-Hydroxy-7-methoxy-5-benzofuranacrylic acid gamma-lactone;6-hydroxy-7-methoxy-5-benzofuranacrylicaciddelta-lactone;6-hydroxy-7-methoxy-5-benzofuranacrylicacidelta-lactone;7-Furocoumarin
8-methoxypsoralen (also known as methoxsalen) is a naturally occurring furocoumarin compound existing in several species of plants such as Psoralea corylifolia.
It is a photoactive substance that can form DNA adducts upon UVA irradiation.
It is a drug used for the treatment of psoriasis, eczema, vitiligo, and some kinds of cutaneous lymphomas associated with the exposure of skin to the UVA or light from lamps or sunlight. Its mechanism of action is through inhibiting the synthesis of the deoxyribonucleic acid (DNA).
After the activation, it can preferentially bind to the guanine and cytosine molecules of DNA, further leading to the cross-linking of DNA, thus inhibiting the DNA synthesis.
It can further inhibit the RNA and protein synthesis at high concentration. It is extracted from Ammi majus.
Appearance & Physical State: Odorless white to cream-colored crystalline solid. Bitter taste followed by tingling sensation.
Melting Point: 143-148ºC
Boiling Point: 414.8ºC at 760mmHg
Flash Point: 204.7ºC
Refractive Index: 1.635
Water Solubility: PRACTICALLY INSOLUBLE
Stability: Stable under normal temperatures and pressures. May decompose when exposed to light.
Storage Condition: Corrosives area. Keep containers tightly closed. Store protected from light. Store in a cool, dry area away from incompatible substances.
Vapor Pressure: 4.33E-07mmHg at 25°C