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White Raw Weight Loss Drugs Material Powder CAS 96829-58-2 Orlipastat

Basic Information
Place of Origin: China
Brand Name: Senwayer Brand
Certification: ISO, 9001, USP
Model Number: 96829-58-2
Minimum Order Quantity: 10grams
Price: Discount is possible if your order is big enough
Packaging Details: 10g, 20g, 50g , 100g, 500g. 1kg, 10kg
Delivery Time: within 2 working days
Payment Terms: T/T in advance, Money Gram, Western Union, Bank Transfer.
Supply Ability: 1000kg/month
Detail Information
CAS: 96829-58-2 Alias: Orlistat , Orlipastat
Apparence: Almost White Crystalline Powder Purity: 99%
Stock: Enough Stock Packing: Foil Bag Or Tin
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Product Description

Pharmaceutical Orlistat Raw Material For Reducing Weight 96829-58-2 White Powder​

 

Quick detail


Product Name: Orlistat
Synonyms: (S)-2-FORMYLAMINO-4-METHYL-PENTANOIC ACID (S)-1-[[(2S,3S)-3-HEXYL-4-OXO-2-OXETANYL]METHYL]-DODECYL ESTER;RO-18-0647;(-)-TETRAHYDROLIPSTATIN;ORLISTAT;N-FORMYL-L-LEUCINE (1S)-1-[[(2S,3S)-3-HEXYL-4-OXO-2-OXETANYL]METHYL]DODECYL ESTER;XENICAL;(-)-Tetrahydrolipstatin(EquivalentToOrlistat);Orlipastat
CAS: 96829-58-2
MF: C29H53NO5
MW: 495.73
Product Categories:

Pharmaceutical Raw Materials;Miscellaneous Biochemicals;API;Antiobesity Agent;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Amino Acids & Derivatives;Heterocycles;ACTOS;Other APIs;Lipid-lowering medicine reducing weight

 

Orlistat Usage


Usage An antiobesity agent. A pancreatic lipase inhibitor. Antiobesity agent.
Usage antidiabetic
Usage Orlistat is an antiobesity agent. Orlistat is an pancreatic lipase inhibitor.
Usage Tetrahydrolipstatin (orlistat) is a semi-synthetic derivative of lipstatin, a metabolite isolated from Streptomyces toxytricini. Tetrahydrolipstatin acts as a potent, irreversible inhibitor of pancreatic lipase. In vivo, it blocks the absorption of triglycerides while allowing fatty acid absorption. Tetrahydrolipstatin is widely used for the treatment of obesity.
Biological Activity Hypolipemic pancreatic, gastric and carboxylester lipase inhibitor. Exhibits no activity at phospholipase A 2 , liver esterase, trypsin and chymotrypsin. Inhibits the thioesterase domain of fatty acid synthase, leading to cell cycle arrest at the G 1 /S boundary in vitro . Prevents the absorption of approximately one third of fat from food and exhibits progastrokinetic, antiobesity and antihypercholesterolemic activity in vivo .

 

Applications:


1. Orlistat is a drug that promotes loss of weight by preventing the digestion and absorption of fat in food. In the intestine, an enzyme called lipase (produced primarily by the pancreas) breaks apart fat in food so that it can be absorbed into the body.
2. Orlistat blocks the action of lipase and thereby prevents the breakup and absorption of fat. Orlistat blocks absorption of about 25% of the fat in a meal. The unabsorbed fat is excreted in the stool.
3. Orlistat is the saturated derivative of lipstatin, a potent natural inhibitor of pancreatic lipases isolated from the bacterium Streptomyces toxytricini. However, due to its relative simplicity and stability, orlistat was chosen over lipstatin for development as an anti-obesity drug.
4. Dietary fats need to be broken down into smaller pieces before the body can absorb them. Orlistat works by blocking the enzyme that breaks down fats in your diet. This undigested fat then passes out of your body in your bowel movement.
5. Orlistat does not block the absorption of calories from sugar and other non-fat foods, so you still need to restrict your total intake of calories.
6.

Orlistat is notorious for its gastrointestinal side effects (sometimes referred to as treatment effects), which can include steatorrhea (oily, loose stools). In the United States and the European Union, orlistat is available for sale without a prescription. Generic formulations of orlistat are available in some countries

 

Orlistat COA


tems Specification Items Result
Appearance white or almost white crystalline powder,smell less White crystalline powder
Melting Point 42.0~46.0°C Confirmed
Specific Rotation -31°~-39°(CHCl3,C=1) Confirmed
Identification The result of HPLC is consisitent to the reference one. The result of IR is consisitent to the reference one. Confirmed
Related Substances ≤ 0.5% ≤ 0.05%
Total impurity ≤ 1.0% Confirmed
Single impurity ≤ 0.1% Confirmed
  ≤ 290ppm Confirmed
  ≤ 5000ppm Confirmed
Residual on Ignition ≤0.1% Confirmed
Sulphate ≤ 0.05% Confirmed
Heavy Metal ≤ 20ppm Confirmed
Purity ≤ 99.0% ~ 99.9% Confirmed

 

White Raw Weight Loss Drugs Material Powder CAS 96829-58-2 Orlipastat 0

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