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Progestin Medical Raw Hormone Powders CAS 152-62-5 Isopregnenone Dehydroprogesterone

Basic Information
Place of Origin: China
Brand Name: Senwayer Brand
Certification: ISO, 9001, USP
Model Number: 152-62-5
Minimum Order Quantity: 1KG
Price: Discount is possible if your order is big enough
Packaging Details: 50kg / Drum
Delivery Time: within 2 working days
Payment Terms: T/T in advance, Money Gram, Western Union, Bank Transfer.
Supply Ability: 1000kg/month
Detail Information
CAS: 152-62-5 Purity: ≥99%
Packing: As Your Requirement Storage Conditions: Avoid Light, Vacuum Airtight Preservation
Stock: In Stock Apparence: White Crystalline / Liquid
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chemical raw material

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medical raw material


Product Description

Progestin Medical Raw Hormone Powders CAS 152-62-5 Isopregnenone Dehydroprogesterone

 


Quick detail


Product Name:  Isopregnenone , Dehydroprogesterone
Synonyms: ;(9β,10α)-pregna-4,6-diene-3,20-dione;10alpha-isopregnenone;10α-pregna-4,6-diene-3,20-dione;20-dione,(9-beta,10-alpha)-pregna-6-diene-3;20-dione,(9beta,10alpha)-pregna-6-diene-3;6-dehydro-9beta,10alpha-progesterone;6-dehydro-retroprogesteron
CAS: 152-62-5
MF: C21H28O2
MW: 312.45
EINECS: 205-806-8

Density: 1.1g/cm3
Melting Point: 168-173ºC
Boiling Point: 462.8ºC at 760mmHg
Flash Point: 172.2ºC
Refractive Index: 1.556
Vapor Pressure: 9.55E-09mmHg at 25°C

 

Description


It has selective progestational activity and does not inhibit ovulation. The greater rigidity of also positively affects its selectivity, while natural progesterone is less selective, existing in different conformations that more easily bind to different receptors. As a consequence of its better bioavailability and the progestational activity of its main metabolites (20-, 21- and 16-hydroxy derivatives), the equivalent dose of is 10–20 times lower than that of oral micronized progesterone.

 

Medical uses


It has proven effective in a variety of conditions associated with progesterone deficiency,  Infertility due to luteal insufficiency  including threatened miscarriage, habitual or recurrent miscarriage, Menstrual disorders premenstrual syndrome,  and endometriosis. Dydrogesterone has also been registered as a component of menopausal hormone therapy to counteract the effects of unopposed estrogen on the endometrium in women with an intact uterus.

 

Application


1 . Uses central stimulant, convulsant
2 . Uses A synthetic progestin largely used in hormone therapy, on the central nervous system by studying two markers of the neuroendocrine function: the neurosteroid allopregnanolone and the opioid .beta.-endorphin. Progestogen.

3 . is used as an effective, orally active progestogen for gynaecological conditions related to a wide variety of progesterone deficiencies in pregnant women. The molecular structure and pharmacological effects are somewhat similar to endogenous progesterone, although in smaller amounts it is found to be orally active. Its freedom from hormonal effects like those related to corticoid, androgenic, estrogenic, anabolic, and other effects gives an advantage over other synthesized progestogens.
4 . when used therapeutically is closely related to its physiological action on the neuro-endocrine control of ovarian function, as well as on the endometrium. This is an indication in all cases of endogeneous progesterone deficiency - relative or absolute. The molecule was licensed for use in several indications, including threatened or recurrent miscarriage, dysfunctional bleeding, infertility due to luteal insufficiency, dysmenorrhea, endometriosis, secondary amenorrhoea, irregular cycles, pre-menstrual syndrome and also as a hormone replacement therapy.

 

Progestin Medical Raw Hormone Powders CAS 152-62-5 Isopregnenone Dehydroprogesterone 0

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