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Pharmaceutical Raw Material Drug Memantine Hydrochloride HCl Powder CAS 41100-52-1

Basic Information
Place of Origin: China
Brand Name: Senwayer
Certification: ISO, 9001, USP
Model Number: 41100-52-1
Minimum Order Quantity: 1grams
Price: Discount is possible if your order is big enough
Packaging Details: 10g, 20g, 50g , 100g, 500g. 1kg, 10kg
Delivery Time: within 2 working days
Payment Terms: T/T in advance, Money Gram, Western Union, Bank Transfer.
Supply Ability: 10kg/month
Detail Information
Model: 41100-52-1 Apparence: White Or White-like Crystal Powder
Grade: Pharma Grade Stock: Enough Stock
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Product Description

Pharmaceutical Raw Materials Memantine Hydrochloride HCl Powder CAS 41100-52-1

 

Details


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Memantine HCl


Synonyms: Memantine HCL;1,3-Dimethyl-5-Aminoadamantane Hydrochloride;1,3-Dimethylaminoadamantane Hydrochloride;1-Amino-3,5-Dimethyladamantane Hcl;1-Amino-3,5-Dimethyladamantane Hydrochloride;1-Amino-3,4-Dimethyladamantane Hydrochloride
CAS: 41100-52-1
MF:C12H22ClN
MW:215.76
EINECS:255-219-6
Melting point:292 °C
Chemical Properties:White Crystalline Solid

 

Usages


Usages 1.   Used as an antiparkinsonian and antispasmodic.
Usages 2.   Product Categories: Adamantane derivatives;Antispasmodic;Antiparkinsonian;Adamantanes;Intermediates & Fine Chemicals;Pharmaceuticals;Glutamate receptor;Glutamate;Amines;API;Other APIs;raw materials
hemical Properties Crystalline Solid
Usages 3.   Used as an antiparkinsonian and antispasmodic
Usages 4.   Antiparkinsonian;Dopaminergic agonist
Usages 5.   Anti Alzheimer's

 

Description


Memantine HCl is the HCl form of Memantine. Memantine is a well- known neuroprotective drug used for the treatment of Alzheimer's disease. It is believed to be the first neuroprotective drug that has achieve clinical approval by US FDA as well as European. The development of Alzheimer's disease involves the misfolded mutant proteins such as β-amyloid peptide (Aβ, particularly Aβ1−42). These misfolded mutant protein can increase the NMDA response and further cause severe excitotoxicity. Memantine suppresses this process through acting as the antagonist of the N-methyl-d- aspartate-sensitive glutamate receptor (NMDARs). Memantine is also under investigation as a potential treatment for other kind of neurodegenerative disorders such as HIV-associated dementia, neuropathic pain, glaucoma, depression, Huntington's disease, ALS and movement disorders, among other.

Memantine HCL is an oral medication for the treatment of moderate to severe dementia associated with Alzheimer's. Memantine HCL's effects are independent of acetylcholine and acetylcholinesterase.

 

Application


It is believed that too much stimulation of nerve cells by glutamate may be responsible for the degeneration of nerves that occurs in some neurological diseases such as Alzheimer's disease. Glutamate is produced and released by nerve cells in the brain. The released glutamate then travels to nearby nerve cells where it attaches to a receptor on the surface of the cells called the N-methyl-D-aspartate (NMDA) receptor.

Memantine HCL blocks this receptor and thereby decreases the effects of glutamate. It is thought that by blocking the NMDA receptor and the effects of glutamate, memantine may protect nerve cells from excess stimulation by glutamate.

 

Main use


Memantine hydrochloride is a kind of pharmaceutical raw materials, into a tablet called "easy times Shen, the product should be on the diagnosis and treatment of Alzheimer type dementia experienced prescription and guide the patients to use. There are patients with medication on time to supervise the case of starting treatment of caregivers. Dementia should be diagnosed in accordance with current diagnostic criteria and guidelines.

 

Pharmaceutical Raw Material Drug Memantine Hydrochloride HCl Powder CAS 41100-52-1 0

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