|Place of Origin:||China|
|Brand Name:||Senwayer Brand|
|Certification:||ISO, 9001, USP|
|Minimum Order Quantity:||10g|
|Price:||Discount is possible if your order is big enough|
|Packaging Details:||10g, 20g, 50g , 100g, 500g. 1kg, 10kg|
|Delivery Time:||within 2 working days|
|Payment Terms:||T/T in advance, Money Gram, Western Union, Bank Transfer.|
|Supply Ability:||50KG / Month|
|Apparence:||White Crystalline Powder||Purity:||99%|
|Grade:||Pharma Grade||Packing:||As Your Requirement|
chemical raw material,
medical raw material
Pharmaceutical Raw Powder Loperamide Hydrochloride 34552-83-5 Gastrointestinal Drugs
|Synonyms:||loperamide HCl: Lopemid; LoperaMide Hydrochloride; Imodium; 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide, hydrochloride; Suprasec; Loperamide hydrochloride; Loperyl; Fortasec; Loperamide HCl; Dissenten; Lopemin;|
|Appearance||Crystals, practically insoluble in water|
|Boiling Point:||647.2ºC at 760 mmHg|
Loperamide is the generic form of the brand-name drug Imodium, a medication used to treat diarrhea.
Imodium works by slowing down the movement of the gut. This decreases the number of bowel movements and makes stool less watery.
Imodium may also be used to decrease the amount of discharge in patients who have undergone an ileostomy(a procedure to move waste out of the body when the colon or rectum is not working properly) or to treat people with inflammatory bowel disease (IBD).
|Usage||Labeled Loperamide, which is used as an antidiarrheal|
|Usage||Ca channel blocker|
|Biological Activity||High affinity μ -opioid receptor agonist with peripheral selectivity (K i values are 2, 48 and 1156 nM for μ -, δ - and κ -opioid receptors respectively). Antidiarrhoeal and antihyperalgesic agent. Also a Ca 2+ channel blocker; at low micromolar concentrations it blocks broad spectrum neuronal HVA Ca 2+ channels and at higher concentrations it reduces Ca 2+ flux through NMDA receptor operated channels.|
How it Works
Loperamide hydrochloride causes the activity within the intestines to slow down. It also alters the movement of both electrolytes and water through the bowels. According to Drugs.com, it may take as many as 48 hours for the medicine to control diarrhea symptoms.