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Pain Relieving Phenacetin

Basic Information
Place of Origin: China
Brand Name: Senwayer Brand
Certification: ISO, 9001, USP
Model Number: 62-44-2
Minimum Order Quantity: 10grams
Price: Discount is possible if your order is big enough
Packaging Details: 10g, 20g, 50g , 100g, 500g. 1kg, 10kg
Delivery Time: within 2 working days
Payment Terms: T/T in advance, Money Gram, Western Union, Bank Transfer.
Supply Ability: 1000kg/month
Detail Information
CAS: 62-44-2 Alias: Phenacetin, Fenacetina
Apparence: Almost White Crystalline Powder Purity: 99%
Usage: Pain Relieving Fever-Reducing Drugs Grade: Pharma Grade
Stock: Available Deliver Time: 5 TO 7 Working Days
High Light:

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Product Description

Pain Relieving Fever-Reducing Drugs Medicine Phenacetin Local Anesthetic Drugs 62-44-2
 
Quick detail


Phenacetin
CAS No.:

62-44-2

Synonyms:

p-Acetophenetidide; Acetamide, N-(4-ethoxyphenyl)-; Achrocidin; p-ethoxyacetanilide; Codempiral; 4'-ethoxyacetanilide; Acetphenetidin; N-(4-ethoxyphenyl)acetamide; Phenacetin; Contradouleur; Acetophenetidine; Acetophenetin; Acetophenetidin;

Formula: C10H13NO2
Exact Mass: 179.09500
Molecular Weight: 179.21600
PSA: 38.33000
LogP: 2.11670
Properties

Appearance & Physical State: white crystalline powder
Density: 1.099 g/cm3
Melting Point: 133-138ºC
Boiling Point: 132 °C / 4mmHg
Refractive Index: 1.505 (20ºC)
Water Solubility: 0.076 g/100 mL
Stability: Stable. Incompatible with strong oxidizing agents, strong acids.
Storage Condition: 2-8ºC

 

Phenacetin Description:


Phenacetin (or acetophenetidin) is a pain-relieving and fever-reducing drug, which was widely used between its introduction in 1887 and the 1983 ban imposed by the FDA on its use in the United States. Its use has declined because of its adverse effects, which include increased risk of certain cancers and kidney damage. It is metabolized as paracetamol (acetaminophen), which replaced it in some over-the-counter medications following the ban on phenacetin.

 

Phenacetin Usage

Usage 1 Analgesic, antipyretic. Component of APC tablets, analgesic mixture also containing aspirin and caffeine. Phenacetin is reasonably anticipated to be a human carcinogen; analgesic mixtures containing Phenacetin are listed as known human carcinogens.
Usage 2 glycosylation inhibitor
Usage  3

Used for organic synthesis of raw materials and drug intermediates from acetaminophen ether.

Usage  4 Antipyretic analgesics for the treatment of fever, headache, neuralgia.
Usage  5 Active pharmaceutical ingredient for Scientific Research.

 

Phenacetin Application:


Those who have taken drugs that contain phenacetin are more likely to develop cardiovascular disease, high blood pressure, anemia and cancer, and they are at a higher risk of death because of renal failure or diseases of the urinary system, according to various studies.

 

A 1989 study showed that daily users of phenacetin were 5.1 times more likely to develop kidney disease than people who used the drug infrequently. The drug, which was also used in veterinary medicine, was shown to cause benign and malignant tumors in both mice and rats during experimental laboratory studies.

 

Some over-the-counter painkiller manufacturers replaced phenacetin with paracetamol, a similar drug that has not been shown to be a carcinogen. Paracetamol is also known as acetaminophen. Studies have shown that acetaminophen also can cause damage to the kidneys, but its side effects are not as serious as those of phenacetin.

 

Phenacetin COA


Product name Phenacetin
CAS No. 62-44-2 Outer Packing 25KG
Production date 2016.05.07 Shelf life 2019.05.05
Standard adopted BP68
Items of analysis Specification Results
Description Should comply with the standard Comforms
Identification Positive Positive
Melting point 134℃ to 136.5℃ 134.5℃ to 136.5℃
4-chloroacetanilide BP1968 <3.5ml/ 0.6g
P-Phenetidine BP1968 Comforms
Sulphated ash ≤0.1% 0.07%
Assay ≥99% 99.1%
through a uss# 80   98%
Conclusion Qualified

 

Pain Relieving Phenacetin 0

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