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Healthy CAS 51372-29-3 Budesonide Powder For Crohn'S Disease Treatment

Basic Information
Place of Origin: China
Brand Name: Senwayer Brand
Certification: ISO, 9001, USP
Model Number: 51372-29-3
Minimum Order Quantity: 10grams
Price: Discount is possible if your order is big enough
Packaging Details: 10g, 20g, 50g , 100g, 500g. 1kg, 10kg
Delivery Time: within 2 working days
Payment Terms: T/T in advance, Money Gram, Western Union, Bank Transfer.
Supply Ability: 1000kg/month
Detail Information
CAS: 51372-29-3 Alias: Budesonide , Dexbudesonide
Apparence: Almost White Crystalline Powder Purity: 99.5%
Packing: As Your Requirement Stock: Enough Stock
High Light:

anti inflammatory medications

,

anti histaminic drugs


Product Description

Oral Medical Budesonide Dexbudesonide 51372-29-3 For Treating Crohn's Disease

 

Quick detail


Product name: Budesonide . Dexbudesonide
CAS NO. 51372-29-3
Molecular Weight: 430.53386 [g/mol]
Molecular Formula: C25H34O6
Index of Refraction: 1.592
Molar Refractivity: 113.86 cm3
Molar Volume: 336.4 cm3
Surface Tension: 55.2 dyne/cm
Density: 1.27 g/cm3
Flash Point: 201.8 °C
Enthalpy of Vaporization: 102.44 kJ/mol
Boiling Point: 599.7 °C at 760 mmHg
Vapour Pressure: 6.94E-17 mmHg at 25 °C

 

Budesonide​ Introduction


Budesonide is a synthetic (man-made) steroid of the glucocorticoid family that is used for treating Crohn's disease.

 

Budesonide is available as a generic drug.

 

Budesonide is used to treat an inflammatory bowel disease called Crohn's disease. This medicine works inside the intestine(bowel) to reduce inflammation and symptoms of the disease. It also helps keep the symptoms of Crohn's disease from coming back. Budesonide is a steroid (cortisone-like) medicine.

 

Budesonide Usage


  • Budesonide is used for the treatment of mild-to-moderately-active Crohn's disease involving the ileum (the second half of the small intestine) and/or ascending colon (the beginning of the large intestine). It is approved for maintaining remissions for up to three months.
  • Budesonide also is used for the induction of remission in patients with active, mild to moderate ulcerative colitis.
  • Budesonide rectal foam is used for the induction of remission in patients with active mild to moderate distalulcerative colitis extending up to 40 cm from the anus.

 

What is the dosage for budesonide ?


  1. The recommended dose for active Crohn's disease is 9 mg once daily in the morning for up to 8 weeks.
  2. The 8 week course may be repeated for recurring episodes.
  3. The dose for maintenance of remission is 6 mg once daily for 3 months.
  4. The recommended dosage for the induction of remission in adult patients with active, mild to moderateulcerative colitis is one 9 mg extended release tablet to be taken once daily in the morning for up to 8 weeks.
  5. The recommended dose for the spray is 1 spray administered twice daily for 2 weeks followed by 1 spray once daily for 4 weeks.

Which drugs or supplements interact with budesonide ?


Medicines which block the liver enzymes that break down budesonide may lead to higher blood concentrations and more side effects of budesonide. Such medications include

  • ketoconazole (Nizoral),
  • fluconazole (Diflucan),
  • itraconazole (Sporanox),
  • clarithromycin (Biaxin),
  • erythromycin,
  • verapamil (for example, Calan; Isoptin; Covera HS),
  • diltiazem (for example, Cardizem; Dilacor),
  • ritonavir (Norvir; Kaletra),
  • indinavir (Crixivan), and
  • saquinavir (Invirase, Fortovase).

How does budesonide work?


The naturally-occurring hormone whose actions budesonide mimics, is cortisol or hydrocortisone which is produced by the adrenal glands.

Glucocorticoid steroids have potent anti-inflammatory actions. Crohn's disease is a chronic inflammatory bowel disease of unknown cause that results in diarrhea, crampy abdominal pain,fever and bleeding from the rectum.

The active ingredient in Budesonide, is released from granules in the ileum of the small intestine and the right (proximal) colon, where the inflammation of Crohn's disease occurs.

Budesonide acts directly by contact with the ileum and colon. Budesonide that is absorbed into the body travels first to the liver where it is broken-down and eliminated from the body.

This prevents the majority of the absorbed drug from being distributed to the rest of the body.

As a result, budesonide causes fewer severe side effects throughout the body than other corticosteroids.

 

Healthy CAS 51372-29-3 Budesonide Powder For Crohn'S Disease Treatment 0

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