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Effective Chlorpheniramine Maleate , Raw Antagonist Histamine Powders CAS 113-92-8

Basic Information
Place of Origin: China
Brand Name: Senwayer Brand
Certification: ISO, 9001, USP
Model Number: 113-92-8
Minimum Order Quantity: 10g
Price: Discount is possible if your order is big enough
Packaging Details: 10g, 20g, 50g , 100g, 500g. 1kg, 10kg
Delivery Time: within 2 working days
Payment Terms: T/T in advance, Money Gram, Western Union, Bank Transfer.
Supply Ability: 50KG / Month
Detail Information
CAS: 113-92-8 MF: C20H23ClN2O4
Apparence: White Crystalline Powder Purity: 99%
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pharmaceutical raw material

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medical raw material


Product Description

Effective Chlorpheniramine Maleate Raw Powders For Antagonist Histamine CAS 113-92-8
 
Quick detail


Name: Chlorpheniramine maleate
CAS No.: 113-92-8
Formula: C20H23ClN2O4
Molecular Weight: 390.86
Synonyms: 2-Pyridinepropanamine,?-(4-chlorophenyl)-N,N-dimethyl- [132-22-9] but the (Z)-2-butenedioate (1:1); Prestwick_57;Allergin;Chlor-trimeton; Teldrin; Piriton; Chlorprophenpyridamine; but-2-enedioic acid; 3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-yl-propan-1-amine;Chlorpheniramine maleate (JP14/USP);[3-(4-chlorophenyl)-3-pyridin-2-yl-propyl]-dimethyl-azanium; (Z)-4-hydroxy-4-oxo-but-2-enoate;Chlor-Tripolon;Neorestamin;Chlor-trimeton (TN);2-Pyridinepropanamine,?-(4-chlorophenyl)-N,- N-dimethyl-,(2Z)-2-butenedioate (1:1);chlorphenamine hydrogen maleate;Teldrin (TN);
EINECS: 204-037-5
Density: 1.107 g/cm3
Melting Point: 130-135 ºC
Boiling Point: 379 ºC at 760 mmHg
Flash Point: 183 ºC
Solubility: 1-5 g/100 mL at 21 ºC
Appearance: White crystalline powder

 

Description


Chlorpheniramine maleate is an active ingredient found in many prescription medications and over-the-counter products used for treating allergies, hives, and the common cold. As an antihistamine, it works by blocking H1 receptors and acetylcholine receptors in the body. The medication comes in tablet, capsule, and liquid form, and is taken by mouth every 4 to 12 hours, depending on the particular product.

 

Usage 


Chlorpheniramine maleate is an antihistamine medication used as an active ingredient in many different non-prescription medicines and prescription drugs.

 

It is used to treat allergies such as hay fever, hives, and the common cold. Chlorpheniramine maleate is one of the two most common forms of the medication (the other is chlorpheniramine tannate).

 

How Does It Work


Chlorpheniramine maleate is part of a class of drugs called antihistamines. Specifically, it is an H1 receptor antagonist. This means that it blocks a specific type of histamine receptor in the body known as H1 receptors. Since allergic reactions are partly caused by the release of histamine from certain cells in the body, chlorpheniramine maleate can help relieve or prevent allergy symptoms.

Chlorpheniramine maleate also blocks acetylcholine receptors, an action that produces some of the unpleasant side effects of the medication, such as dry mouth or difficulty urinating, but also helps to relieve a runny nose.

 

Indications and dosages


➣ Allergy symptoms; management of anaphylaxis and transfusion reactions

  1. Adults: 4 mg q 4 to 6 hours P.O. or 8 to 12 mg P.O. of sustained-release form q 8 to 12 hours. Maximum dosage is 24mg/day.
  2. Children ages 6 to 12: 2 mg P.O. q 4 to 6 hours daily. Maximum dosage is 12 mg/day.

 

Dosage adjustment


• Glaucoma          • Gastric ulcer                    • Hyperthyroidism• Heart disease

 

Specification


Items Specification
Appearance White or almost white powder
Identification Meets the requirements
Specific Rotation -0.10 ~ +0.10°
Water ≤0.5%
Heavy Metals ≤0.002%
Redidue in Ignition ≤0.2%
Related Substances Meets the requirements
Benzene Sulfonic Acid 27.3 ~ 28.7%
Ethanol ≤300ppm
Toluene ≤60ppm
Benzene ≤2ppm
Acetic Acid ≤600ppm
Methylamine ≤20ppm
Ethyl Benzene Sulfonate ≤5ppm
Particle Size Meets the requirements
Assay 98.0 ~102.0%
Standard USP32

Contact Details
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