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Effective Anti Inflammatory Medicine Glucocorticoid Drugs Dexamethasone

Basic Information
Place of Origin: China
Brand Name: Senwayer Brand
Certification: ISO, 9001, USP
Model Number: 50-02-2
Minimum Order Quantity: 10grams
Price: Discount is possible if your order is big enough
Packaging Details: 10g, 20g, 50g , 100g, 500g. 1kg, 10kg
Delivery Time: within 2 working days
Payment Terms: T/T in advance, Money Gram, Western Union, Bank Transfer.
Supply Ability: 1000kg/month
Detail Information
CAS: 50-02-2 MF: C22H29FO5
Apparence: Almost White Powder Purity: 99%
Stock: Enough Stock Grade: Pharma Grade
High Light:

anti inflammatory medications

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anti histaminic drugs


Product Description

Effective Raw Steroid Powder Dexamethasone Anti Inflammatory Medicine CAS 50-02-2

 

Quick detail


Dexamethason

Molecular formula:C22H29FO5

Molecular weight:392.46

EINECS:200-003-9

Purity:min 98%

Appearance:White powder

Melting Point:262-264 °C(lit.)

Alpha:75 º (c=1, dioxane)

Refractive index:76 ° (C=1, Dioxane)

Storage temp. :2-8°C

Solubility:ethanol: 1 mg/mL

Water Solubility:10 mg/100 mL (25 ºC)

Stability:Stable. Combustible. Incompatible with strong oxidizing agents, strong bases, acid anhydrides, acid chlorides. May be light sensitive.

 

Introduction of Dexamethasone


Dexamethasone is reacted with a source of hypobromite, such as basic N-bromosuccinimide, to form the 9α-bromo-11β-hydrin derivative, which is then ring-closed to an epoxide. A ring-opening reaction with hydrogen fluoride in tetrahydrofuran gives dexamethasone.

 

Dexamethasone, a corticosteroid, is similar to a natural hormone produced by your adrenal glands. It often is used to replace this chemical when your body does not make enough of it. It relieves inflammation (swelling, heat, redness, and pain) and is used to treat certain forms of arthritis; skin, blood, kidney, eye, thyroid, and intestinal disorders (e.g., colitis); severe allergies; and asthma. Dexamethasone is also used to treat certain types of cancer.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

 

Use of Dexamethasone


Dexamethasone is used to treat many inflammatory and autoimmune conditions. If given in high doses, it is useful to counteract allergic anaphylactic shock. It is used in transvenous screw-in cardiac pacing leads to minimize the inflammatory response of the myocardium. In oncology, it is given to cancer patients undergoing chemotherapy to counteract certain side-effects of their antitumor treatment. It is also used in the treatment of high altitude cerebral edema as well as pulmonary edema. Dexamethasone is also used in a diagnostic context namely in its property to suppress the natural pituitary-adrenal axis.

 

Dexamethasone is used for reducing inflammation in many conditions. Some examples include:

  • rheumatoid arthritis,
  • systemic lupus,
  • acute gouty arthritis,
  • psoriatic arthritis,
  • ulcerative colitis, and
  • Crohn's disease.

Severe allergic conditions that fail to respond to other treatments also may respond to dexamethasone. Examples include:

  • bronchial asthma,
  • allergic rhinitis,
  • drug-induced dermatitis, and
  • contact and atopic dermatitis.
  • Chronic skin conditions treated with dexamethasone include:
  • dermatitis herpetiformis,
  • pemphigus,
  • severe psoriasis, and
  • severe seborrheic dermatitis.

Side effect of Dexamethasone


Dexamethasone may have such sife effects:

1)
Stomach upset, increased sensitivity to stomach acid to the point of ulceration of esophagus, stomach, and duodenum.
2) Increased appetite leading to significant weight gain
3)
A latent diabetes mellitus often becomes manifest, glucose intolerance is worsened in patients with pre-existing diabetes
4)
Immunsuppressant action, particularly if given with other immunosuppressants, such as cyclosporine, may allow bacterial, viral, and fungal disease to progress more easily and can become life-threatening; fever as a warning symptom is often suppressed.
5)
Psychiatric disturbances, including personality changes, irritability, euphoria, or mania and mood swings.

 

 

Effective Anti Inflammatory Medicine Glucocorticoid Drugs Dexamethasone 0

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