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API Cancer Cure Drug Doxorubicin Hydrochloride CAS 25316-40-9 White Powder

Basic Information
Place of Origin: China
Brand Name: Senwayer
Certification: ISO, 9001, USP
Model Number: 25316-40-9
Minimum Order Quantity: 10grams
Price: Discount is possible if your order is big enough
Packaging Details: 10g, 20g, 50g , 100g, 500g. 1kg, 10kg
Delivery Time: within 2 working days
Payment Terms: T/T in advance, Money Gram, Western Union, Bank Transfer.
Supply Ability: 1000kg/month
Detail Information
CAS: 25316-40-9 Alias: Doxorubicin Hydrochloride
Apparence: Almost White Crystalline Powder Purity: 99.5%
High Light:

anti cancer drugs

,

antineoplastic drugs


Product Description

Anti-cancer Doxorubicin hydrochloride 25316-40-9 Raw Material Drug API Powder


 
Quick detail

 

Product name: Doxorubicin hydrochloride
Synonyms:Adriamycin
Usage: Topoisomerase II inhibitor. Antibiotic with cytotoxic actions.
CAS number:25316-40-9
Purity:≥99%
MW:580.0
MF:C27H29NO11•HCl
Appearance: A red-orange, crystalline powder
Solubility. Soluble in DMSO to 25 mM and in water to 50 mM
Category: Cytotoxic drug
Storage: Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

 



Basic information
 
Packing: 1)Aluminum Foil Bag: 100g, 500g, 1Kg 2)Fiber Drum: 25Kg
Delivery Method: HKEMS, DHL, TNT, UPS, FEDEX, EMS, China Air Post etc.
Clearance Rate: 100% Custom Pass, Diguised Package and Safe Delivery
Delivery Time: 5-14 Working Days, Tracking Number Available
Payment Terms: T/T, MoneyGram, Western Union and Bitcoin
Origin: Hubei Province, China
Brand Name: Senwayer Brand
Production Capacity:  1000Kg/Month

 


 
Doxorubicin Hydrochloride Description:

 

Doxorubicin Hydrochloride is the hydrochloride salt of doxorubicin, an anthracycline antibiotic with antineoplastic activity. Doxorubicin, isolated from the bacterium Streptomyces peucetius var. caesius, is the hydroxylated congener of daunorubicin. Doxorubicin intercalates between base pairs in the DNA helix, thereby preventing DNA replication and ultimately inhibiting protein synthesis. Additionally, doxorubicin inhibits topoisomerase II which results in an increased and stabilized cleavable enzyme-DNA linked complex during DNA replication and subsequently prevents the ligation of the nucleotide strand after double-strand breakage. Doxorubicin also forms oxygen free radicals resulting in cytotoxicity secondary to lipid peroxidation of cell membrane lipids; the formation of oxygen free radicals also contributes to the toxicity of the anthracycline antibiotics, namely the cardiac and cutaneous vascular effects.

 


 
Doxorubicin Hydrochloride Application


1. Hodgkin's disease and lymphosarcoma, reticulum cell sarcoma.
2. undifferentiated small cell and non-small cell lung cancer, breast cancer.
3. acute lymphoblastic and myeloid leukemia.
4. osteosarcoma and soft tissue sarcoma.
5. ovarian cancer, testicular cancer, bladder cancer, . Wilms cancer, prostate cancer, thyroid cancer, neuroblastoma cancer, esophageal cancer, stomach cancer, liver cancer, cervical cancer and head and neck cancer. Multiple myeloma, pancreatic cancer, endometrial cancer and brain tumors can also be applied.

 


 

Doxorubicin Hydrochloride COA:

 


Product Name
Doxorubicin hydrochloride(C27H30ClNO11) CAS:25316-40-9
Items Tested Specification Result
Purity 98.0~102.0% 99.02%
Description
Orange-red or red crystalline powder; No visible
evidence of contamination by foreign matter.

Confirm
Identification A IR spectrum corresponds to the IR spectrum of the reference standard Confirm
Identification B
The retention time of the doxorubicin peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay.

Confirm
Solubility Soluble in water and methanol; slightly soluble in ethanol; practically insoluble in acetone. Conforms
     
Acetone ≤ 0.5% 0.31%
Acetone +Ethanol ≤ 2.5% 0.60%
methanol ≤ 0.3% Not detected
Dichloromethane ≤ 0.06% Not detected
pH 4.0 to 5.5 5.1
Water Content ≤ 4.0% 0.8%
Related Substances    
Impurity A (Doxorubicinone) ≤ 0.5% 0.1%
Any Other unknown Impurity ≤ 0.1% 0.07%
Total unknown Impurities ≤ 0.3% 0.2%
Total Impurities ≤ 1.0% 0.9%
Conclusion It complies to reference standard
 

 


 

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Contact Details
senwayer

WhatsApp : +8617764031156