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API Active Pharmaceutical Ingredients Antiemetic Domperidone CAS 57808-66-9

Basic Information
Place of Origin: China
Brand Name: Senwayer Brand
Certification: ISO, 9001, USP
Model Number: 57808-66-9
Minimum Order Quantity: 10grams
Price: Discount is possible if your order is big enough
Packaging Details: 10g, 20g, 50g , 100g, 500g. 1kg, 10kg
Delivery Time: within 2 working days
Payment Terms: T/T in advance, Money Gram, Western Union, Bank Transfer.
Supply Ability: 1000kg/month
Detail Information
CAS: 57808-66-9 MF: C22H24ClN5O2
Apparence: White Crystalline Powder Purity: 99%
Usage: Antiemetic Domperidone Stock: Enough Stock
High Light:

pharmaceutical raw chemical

,

active pharmaceutical ingredients


Product Description

Healthy Domperidone For Anti-Vomiting Lactation Antiemetic CAS 57808-66-9 API Drugs
 
Quick detail


Domperidone
CAS No.: 57808-66-9
Synonyms: 6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-benzimidazol-2-one;
Formula: C22H24ClN5O2
Exact Mass: 425.16200
Molecular Weight: 425.91100
PSA: 78.82000
LogP: 3.29110
Appearance white powder
Density: 1.341 g/cm3
Melting Point: 242.5ºC
Stability: Stable. Incompatible with strong oxidizing agents.
Storage Condition: Keep tightly closed.


 

Domperidone Description


  1. A novel peripheral dopamine receptor antagonist that does not cross the blood-brain barrier; anti-emetic. Domperidone(Motilium) is a dopamine blocker and an antidopaminergic reagent.
  2. Domperidone is a commonly used antiemetic and gastro-kinetic drug with its appearance being white to light yellow powder and bitter taste. It is almost insoluble in water, slightly soluble in ethanol, easily soluble in lactic acid as well as soluble in citrate. This product is a kind of peripheral dopamine receptor antagonists with strong action.
  3. Domperidone can block the DA1 and DA2 receptor next to the synapses, antagonizing the inhibitory effect of dopamine on the postsynaptic cholinergic neurons of myenteric plexus and causing the stomach contractions. It can promote the motility and tension of digestive tract motility to return to normal function, promoting the emptying of stomach, increasing the motility of gastric antral and duodenum, coordinating the contraction of the pylorus as well as enhancing the esophageal peristalsis and the tension of the lower esophageal sphincter.

 
Domperidone Usage


1 Domperidone is used to help to move food faster through your food pipe (oesophagus), stomach and gut. This is so that it does not stay in the same place for too long.
2 It is a dopamine agonist, and belongs to a group of medicines known as anti-emetics.
3 In general this drug is used to relieve symptoms of feeling sick (nausea) and sickness (vomiting).
4 Benefits of being on this drug can include relieving symptoms of nausea and vomiting.

 

API Active Pharmaceutical Ingredients Antiemetic Domperidone CAS 57808-66-9 0
 

DOMPERIDONE SIDE EFFECTS


  1. Unusual production of breast milk in men and women,
  2. breast enlargement in men and women,
  3. lowering of sexual drive (libido) in men,
  4. menstrual periods may be irregular or stop,
  5. problems with vision,
  6. development of a tremor,
  7. imbalance.

If any of these persist or you consider them severe then inform your doctor or pharmacist.

Contact Details
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