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API-2 Akt / PKB Signaling Cancer Cure Drug Akt Inhibitor V Triciribine CAS 35943 35 2

Basic Information
Place of Origin: China
Brand Name: Senwayer Brand
Certification: ISO, 9001, USP
Model Number: 35943-35-2
Minimum Order Quantity: 10grams
Price: Discount is possible if your order is big enough
Packaging Details: 10g, 20g, 50g , 100g, 500g. 1kg, 10kg
Delivery Time: within 2 working days
Payment Terms: T/T in advance, Money Gram, Western Union, Bank Transfer.
Supply Ability: 1000kg/month
Detail Information
CAS: 35943-35-2 Apparence: White Powder
Purity: 99% Other Name: Akt Inhibitor V Triciribine, API-2 Akt/PKB
Function: Cancer Cure Drug Stock: Enough Stock
High Light:

anti cancer drugs

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breast cancer drugs


Product Description

Akt Inhibitor V Triciribine CAS 35943-35-2 API-2 Akt/PKB Signaling Cancer Cure Drugs

 

Quick detail


Product name : Triciribine

Description : Selective, potent inhibitor of Akt activation

Alternative names : API 2: NSC 154020: TCN

Biological description: Cell-permeable tricyclic nucleoside that inhibits the phosphorylation, activation and signalling of Akt. Selective over PKC, PKA, SGK and p38 pathways. Induces cell growth arrest and apoptosis in vitro.

Purity: > 98%

 

Description


A cell-permeable and reversible tricyclic nucleoside that selectively inhibits the cellular phosphorylation/activation of Akt1/2/3. It does not inhibit known upstream activators of Akt, i.e. PI3K or PDK. Exhibits little effect towards cellular signaling pathways mediated by PKC, PKA, SGK, Stat3, p38, ERK1/2, or JNK. Shown to preferentially induce apoptosis and growth arrest in cancer cells with aberrant Akt activity both in vitro (≥ 60% in cell proliferation at 20 µM) and in vivo (≥ 80% inhibition in tumor growth in mice at 1 mg/kg/day, i.p.). Also available in InSolution™ format.

 

Properties
Density: 2.02g/cm3
Boiling Point: 718.5ºC at 760mmHg
Flash Point: 388.3ºC
Refractive Index: 1.928

 

Application


Akt Inhibitor V, Triciribine, CAS 35943-35-2, is a cell-permeable, selective, reversible inhibitor of the cellular phosphorylation/activation of Akt1/2/3.

 

Research areas


Signal Transduction Protein Phosphorylation Ser / Thr Kinases PKB / AKT Biochemicals Chemical Type Biochemicals Biochemicals Chemical Type Nucleoside Biochemicals Pharmacology Enzymes Kinase Akt Inhibitors Biochemicals Pharmacology Signaling Signal transduction PI3K/Akt signaling Akt Inhibitors Biochemicals Research Area Cancer Signal transduction PI3K/Akt signaling Akt Inhibitors

 

API-2 Akt / PKB Signaling Cancer Cure Drug Akt Inhibitor V Triciribine CAS 35943 35 2 0API-2 Akt / PKB Signaling Cancer Cure Drug Akt Inhibitor V Triciribine CAS 35943 35 2 1API-2 Akt / PKB Signaling Cancer Cure Drug Akt Inhibitor V Triciribine CAS 35943 35 2 2

Contact Details
senwayer

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