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Anti Inflammatory Medical Prostaglandin E2 , CAS 363-24-6 Dinoprostone Powder

Basic Information
Place of Origin: China
Brand Name: Senwayer Brand
Certification: ISO, 9001, USP
Model Number: 363-24-6
Minimum Order Quantity: 10grams
Price: Discount is possible if your order is big enough
Packaging Details: 10g, 20g, 50g , 100g, 500g. 1kg, 10kg
Delivery Time: within 2 working days
Payment Terms: T/T in advance, Money Gram, Western Union, Bank Transfer.
Supply Ability: 1000kg/month
Detail Information
CAS: 363-24-6 MF: C20H32O5
Apparence: Almost White Powder Purity: 99%
Stock: Enough Stock Grade: Pharma Grade
High Light:

anti inflammatory medications

,

anti histaminic drugs


Product Description

Medical Prostaglandin E2 Dinoprostone CAS 363-24-6 Anti-inflammatory Drugs Powder

 

Quick detail


Name: Dinoprostone
CAS No.: 363-24-6
Formula: C20H32O5
Molecular Weight: 352.47
Synonyms: 5-Heptenoicacid, 7-[3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl]- (8CI);(-)-Prostaglandin E2;(15S)-Prostaglandin E2; Cervidil;Cerviprime;Dinoprostone;Enzaprost E;Minprositin E2;NSC 196514;PGE2;Primiprost;Prostaglandin E2;Prostenon;Prostenone;Prostin (prostaglandin);U 12062;l-Prostaglandin E2;
EINECS: 206-656-6
Density: 1.148 g/cm3
Melting Point: 66-68 °C
Boiling Point: 530.1 °C at 760 mmHg
Flash Point: 288.5 °C
Solubility: ethanol: 1 mg/mL
Appearance: white to pale yellowish-cream powder

 

 

Dinoprostone Description


Prostaglandin E(2) (PGE(2)), a cyclooxygenase (COX) product, is the best known lipid mediator that contributes to inflammatory pain. Nonsteroidal anti-inflammatory drugs (NSAIDs), inhibitors of COX-1 and/or COX-2, suppress inflammatory pain by reducing generation of prostanoids, mainly PGE(2), while they exhibit gastrointestinal, renal and cardiovascular toxicities.

Selective inhibitors of microsomal PGE synthase-1 and subtype-selective antagonists of PGE(2) receptors, particularly EP(1) and EP(4), may be useful as analgesics with minimized side-effects. Protein kinase C (PKC) and PKA downstream of EP(1) and EP(4), respectively, sensitize/activate multiple molecules including transient receptor potential vanilloid-1 (TRPV1) channels, purinergic P2X3 receptors, and voltage-gated calcium or sodium channels in nociceptors, leading to hyperalgesia. PGE(2) is also implicated in neuropathic and visceral pain and in migraine.

Thus, PGE(2) has a great impact on pain signals, and pharmacological intervention in upstream and downstream signals of PGE(2) may serve as novel therapeutic strategies for the treatment of intractable pain.

The most common and most biologically potent of mammalian prostaglandins. Isolated from sheep prostate. Oxytocic; abortifacient.

 

Anti Inflammatory Medical Prostaglandin E2 , CAS 363-24-6 Dinoprostone Powder 0

 

 

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