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Anti Histaminic Raw Material Drug Fexofenadine Hydrochloride CAS 130018-87-0

Basic Information
Place of Origin: China
Brand Name: Senwayer Brand
Certification: ISO, 9001, USP
Model Number: 130018-87-0
Minimum Order Quantity: 10g
Price: Discount is possible if your order is big enough
Packaging Details: 10g, 20g, 50g , 100g, 500g. 1kg, 10kg
Delivery Time: within 2 working days
Payment Terms: T/T in advance, Money Gram, Western Union, Bank Transfer.
Supply Ability: 50KG / Month
Detail Information
CAS: 130018-87-0 MF: C32H40ClNO4
Apparence: White Crystalline Powder Purity: 99%
Synonyms: Fexofenadine; Allegra Grade: Pharma Grade
High Light:

chemical raw material

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medical raw material


Product Description

Pharmaceutical Fexofenadine Hydrochloride CAS 130018-87-0 Allegra Anti Histaminic
 
Quick detail


Name: Fexofenadine hydrochloride
CAS No.: 153439-40-8
Formula: C32H39NO4.HCl
Molecular Weight: 538.13
Synonyms: Fexofenadine;Allegra;Carboxyterfenadine hydrochloride;Fexofenadine HCl;MDL 16,455A;Telfast;
Melting Point: 148-150 °C
Boiling Point: 697.3 °C at 760 mmHg
Flash Point: 375.5 °C
Appearance: off-white crystalline solid

 

Description


Fexofenadine hydrochloride (trade name: Allegra) belongs to a second-generation antihistamine pharmaceutical drug. It is mainly used for the treatment of allergy symptoms including watery eyes, hay fever, nasal congestion, urticaria, runny nose, itching eyes/nose, sneezing, hives, and itching. It is a kind of selectively peripheral H1 blocker. Its mechanism of action in vivo is through preventing the histamine-mediated activation of the H1 receptors, thus alleviating the symptoms related to allergy. Compared to the first-generation antihistamine drug, it is less prone to penetrate the blood-brain barrier, reducing the possibility to cause side effects such as drowsiness.

 

Uses


This combination medication is used to temporarily relieve symptoms caused by thecommon cold, flu, or allergies. It contains 2 medications: fexofenadine andpseudoephedrine. Fexofenadine is an antihistamine that helps relieve watery eyes, itchy eyes/nose/throat, runny nose, and sneezing. Pseudoephedrine is a decongestantthat helps relieve stuffy nose and ear congestion symptoms.

This medication is not recommended for use in children under 12 years of age due to the large amount of pseudoephedrine in it.

 

Anti Histaminic Raw Material Drug Fexofenadine Hydrochloride CAS 130018-87-0 0

 

Specifications


Item Requirement Results
Description White to off-white powder or crystalline powder; bitter taste, odorless White crystalline powder
chloride The solution gives reaction of chloride complies
HPLC The retention time of the main peak of the test solution corresponds to that of reference peak complies
IR The infrared spectrum of the testing solution corresponds to that of reference solution complies
Residual on ignition ≤0.1% max 0.06%
Heavy metals Not more than 0.2% complies
Impurity B Not more than 0.2% Not detected
Water Not more than 0.5% 0.34%
Impurity A Not more than 0.2% 0.03%
decarboxylated degradant Not more than 0.15% 0.05%
Single impurity Not more than 0.1% 0.06%
Total impurities Not more than 0.5% 0.2%
Content of chloride 6.45%~6.75% 6.52%
Assay(Calculated on the anhydrous basis) Not less than98.0% and Not more than102.0% 99.6%
Conclusion:meet the USP Standard

 

Contact Details
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