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Anti Aging Beta Nicotinamide

Basic Information
Place of Origin: China
Brand Name: Senwayer Brand
Certification: ISO, 9001, USP
Model Number: 1094-61-7
Minimum Order Quantity: 10grams
Price: Discount is possible if your order is big enough
Packaging Details: 10g, 20g, 50g , 100g, 500g. 1kg, 10kg
Delivery Time: within 2 working days
Payment Terms: T/T in advance, Money Gram, Western Union, Bank Transfer.
Supply Ability: 1000kg/month
Detail Information
β-NMN CAS: 1094-61-7 β-NMN Alias: Beta-Nicotinamide Mononucleotide, 1094-61-7, Beta-NM ,β-NMN
β-NMN Apparence: Almost White Crystalline Powder β-NMN Purity: 99%
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Product Description

Anti-aging Raw Materials Beta-Nicotinamide Mononucleotide 1094-61-7 Beta-NM β-NMN

 

Quick detail


Product Name Beta-Nicotinamide Mononucleotide
Synonyms

BETA-NMN;Beta-Nicotinamide Mononucleotide;Beta-Nicotinamide Ribose Monophosphate; Nicotinamide-1-Ium-1-Beta-d-Ribofuranoside 5'-Phosphate; Nicotinamide Ribotide; Nicotinamide Mononucleotide; 3-(aminocarbonyl)-1-(5-O-phosphonato-beta-D-ribofuranosyl)pyridinium

CAS 1094-61-7
EINECS 214-136-5
MF C11H15N2O8P
MW 334.22
Chemical Properties White to yellowish lyophilized powder
Assay 97%min
Standard Enterprise Standard
Usage Cosmetic raw material. A product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice . It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation.

 

β-NMN​​ Description


The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca2+ signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD.

 

NMNAT1 is the most widely expressed of three orthologous genes with nicotinamide-nucleotide adenylyltransferase (NMNAT) activity. Genetically engineered mice lacking NMNAT1 die during early embryogenesis, indicating a critical role of this gene in organismal viability.[citation needed] In contrast, mice lacking NMNAT2, which is expressed predominantly in neural tissues, complete development but die shortly after birth. However, NMNAT1 is dispensable for cell viability, as homozygous deletion of this gene occurs in glioblastoma tumors and cell lines. NMNAT enzymatic activity is probably essential at the cellular level, as complete ablation of NMNAT activity in model organisms leads to cellular inviability.

Anti Aging Beta Nicotinamide 0
β-NMN Usage:

A product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice . It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation.

 
 

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