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99% Active Pharmaceutical Ingredients API Chlorpheniramine Maleate CAS 113-92-8

Basic Information
Place of Origin: China
Brand Name: Senwayer Brand
Certification: ISO, 9001, USP
Model Number: 113-92-8
Minimum Order Quantity: 10grams
Price: Discount is possible if your order is big enough
Packaging Details: 10g, 20g, 50g , 100g, 500g. 1kg, 10kg
Delivery Time: within 2 working days
Payment Terms: T/T in advance, Money Gram, Western Union, Bank Transfer.
Supply Ability: 1000kg/month
Detail Information
CAS: 113-92-8 MF: C20H23ClN2O4
Apparence: White Crystalline Powder Purity: 99%
Other Name: D-chlorpheniramine Maleate; Teldrin; Stock: Enough Stock
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Product Description

Antagonist Of The Histamine API Powder Chlorpheniramine Maleate CAS 113-92-8 Drugs
 
Quick detail


Chlorpheniramine Maleate
CAS No.: 113-92-8
Synonyms:

CHLORPHENAMINE MALEATE; d-chlorpheniramine maleate; teldrin; CHLORPHENAMINE MALEATES; Chloropheniramine Maleate; BISACODYL; (+/-)-CHLORPHENIRAMINE MALEATE SALT; (+/-)-CHLORPHENIRAMINE-D6 MALEATE; CHLORPHENIRAMINE HYDROGEN MALEATE; ibioton; 2-Pyridinepropanamine;  CHLOROPHENIRAMINEMALEATE;  c meton;  CHLOROPHENAMINEMALEATE;  CHLORPHENIRAMINE-D4 MALEATE; Chlorpheniramine Maleate; alunex; Puermin; Chlorpheniramine (maleate); Haynon; Chlorphenamine maleate; 2-Pyridinepropanamine, γ-(4-chlorophenyl)-N,N-dimethyl-, (Z)-2-butenedioate (1:1); CHLORPHENAMINE HYDROGEN MALEATE, WHO STANDARD; CHLORPHENIRAMINE MALEATE REFERENCE STANDARD; dexchlorpheniramine maleate; Chlorpheniramine Maleate; lorphen; Chlorpheniramine Maleate Salt; piriex; allergin; piriton; P-CHLORO(2-DIMETHYLAMINOETHYL)BENZYLPYRIDINE MALEATE;

Formula: C20H23ClN2O4
Exact Mass: 390.13500
Molecular Weight: 390.86100
PSA: 90.73000
LogP: 3.53040
Appearance Odorless white crystalline solid or white powder with a bitter taste.
Density: 1.107 g/cm3
Melting Point: 130-135ºC
Boiling Point: 379ºC at 760 mmHg
Flash Point: 183ºC
Storage Condition: Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Vapor Pressure: 2.9E-14mmHg at 25°C

 

Description


Chlorphenamine (INN), also called chlorpheniramine (USAN and former BAN), commonly marketed in the form of chlorphenamine maleate, is a first-generation alkylamine antihistamine used in the prevention of the symptoms of allergic conditions such as rhinitis and urticaria. Its sedative effects are relatively weak compared to other first-generation antihistamines. Chlorphenamine is one of the most commonly used antihistamines in small-animal veterinary practice. Although not generally approved as an antidepressant or anti-anxiety medication, chlorphenamine appears to have these properties as well.
Chlorphenamine is part of a series of antihistamines including pheniramine (Naphcon) and its halogenated derivatives and others including fluorpheniramine, dexchlorpheniramine (Polaramine), brompheniramine (Dimetapp), dexbrompheniramine (Drixoral), deschlorpheniramine, triprolidine (Actifed), and iodopheniramine.
The halogenated alkylamine antihistamines all exhibit optical isomerism, and chlorphenamine in the indicated products is racemic chlorphenamine maleate, whereas dexchlorpheniramine is the dextrorotary stereoisomer.

 

Usage 


Usage Antihistaminic
Usage An antagonist of the histamine H1-receptor
General Description Odorless white crystalline solid or white powder with a bitter taste. pH (2% aqueous solution) 5. pH (1% aqueous solution) 4-5.

 


Reactivity Profile


Reactivity Profile

A halogenated amine, ester. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides.

 

Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.

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