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8-Methoxypsoralen Anti Inflammatory Medicine Antipsoriatic Methoxsalen 298-81-7

Basic Information
Place of Origin: China
Brand Name: Senwayer Brand
Certification: ISO, 9001,
Model Number: 298-81-7
Minimum Order Quantity: 10grams
Price: Discount is possible if your order is big enough
Packaging Details: 10g, 20g, 50g , 100g, 500g. 1kg, 10kg
Delivery Time: within 2 working days
Payment Terms: T/T in advance, Money Gram, Western Union, Bank Transfer.
Supply Ability: 1000kg/month
Detail Information
CAS: 298-81-7 Apparence: White Powder
Purity: 99.5% Stock: Enough Stock
MOQ: As Your Requirements
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Product Description

8-Methoxypsoralen Anti Inflammatory Medicine Antipsoriatic Methoxsalen 298-81-7

 

Quick detail


Product Name: 8-Methoxypsoralen
Synonyms: 2-g)(1)benzopyran-7-one,9-methoxy-7h-furo(;2-g][1]benzopyran-7-one,9-methoxy-7h-furo[;5-Benzofuranacrylic acid, 6-hydroxy-7-methoxy-, delta-lactone;5-Benzofuranacrylicacid,6-hydroxy-7-methoxy-,δ-lactone;6-Hydroxy-7-methoxy-5-benzofuranacrylic acid gamma-lactone;6-hydroxy-7-methoxy-5-benzofuranacrylicaciddelta-lactone;6-hydroxy-7-methoxy-5-benzofuranacrylicacidelta-lactone;7-Furocoumarin
CAS: 298-81-7
MF: C12H8O4
MW: 216.19
EINECS: 206-066-9

 

Description


8-methoxypsoralen (also known as methoxsalen) is a naturally occurring furocoumarin compound existing in several species of plants such as Psoralea corylifolia.

It is a photoactive substance that can form DNA adducts upon UVA irradiation.

It is a drug used for the treatment of psoriasis, eczema, vitiligo, and some kinds of cutaneous lymphomas associated with the exposure of skin to the UVA or light from lamps or sunlight. Its mechanism of action is through inhibiting the synthesis of the deoxyribonucleic acid (DNA).

After the activation, it can preferentially bind to the guanine and cytosine molecules of DNA, further leading to the cross-linking of DNA, thus inhibiting the DNA synthesis.

It can further inhibit the RNA and protein synthesis at high concentration. It is extracted from Ammi majus.


Properties 


Appearance & Physical State: Odorless white to cream-colored crystalline solid. Bitter taste followed by tingling sensation.
Density: 1.368g/cm3
Melting Point: 143-148ºC
Boiling Point: 414.8ºC at 760mmHg
Flash Point: 204.7ºC
Refractive Index: 1.635
Water Solubility: PRACTICALLY INSOLUBLE
Stability: Stable under normal temperatures and pressures. May decompose when exposed to light.
Storage Condition: Corrosives area. Keep containers tightly closed. Store protected from light. Store in a cool, dry area away from incompatible substances.
Vapor Pressure: 4.33E-07mmHg at 25°C

 

Uses


  • Uses  antipsoriatic, pigmentation agent
  • Uses Naturally occurring analog of Psoralen (P839800). Use in treatment of psoriasis and mycosis fungoides.
  • Uses For the treatment of psoriasis and vitiligo
  • Uses Naturally occurring analog of psoralen. Use in treatment of psoriasis and mycosis fungoides
  • Uses A potent suicide inhibitor of cytochrome P-450.

 

8-Methoxypsoralen Anti Inflammatory Medicine Antipsoriatic Methoxsalen 298-81-7 0

 

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